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4AVX

Hepatocyte Growth Factor-Regulated Tyrosine Kinase Substrate (Hgs-Hrs) bound to an IP2 compound at 1.68 A Resolution

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
HEPATOCYTE GROWTH FACTOR-REGULATED TYROSINE KINASE SUBSTRATEpolymer22626047.91UniProt (O14964)
Pfam (PF00790)
Pfam (PF01363)
HOMO SAPIENS (HUMAN)
2B, F, G, H, I...
(A)
1,2-ETHANEDIOLnon-polymer62.18Chemie (EDO)
3C, D
(A)
ZINC IONnon-polymer65.42Chemie (ZN)
4E
(A)
PHOSPHORIC ACID MONO-(2,3,4,6-TETRAHYDROXY-5-PHOSPHONOOXY-CYCLOHEXYL) ESTERnon-polymer340.11Chemie (ITP)
5M
(A)
waterwater18.0148Chemie (HOH)
Sequence modifications
A: 1 - 225 (UniProt: O14964)
PDBExternal DatabaseDetails
Ser 0-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight26047.9
Non-Polymers*Number of molecules11
Total formula weight967.5
All*Total formula weight27015.4
*Water molecules are not included.

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PDB entries from 2024-10-30

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