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4AU7

The structure of the Suv4-20h2 ternary complex with histone H4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A, B
(A, B)
HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H2polymer24728162.12UniProt (Q6Q783)
Pfam (PF00856)
MUS MUSCULUS (HOUSE MOUSE)SUPPRESSOR OF VARIEGATION 4-20 HOMOLOG 2, SU(VAR)4-20 HOMOLOG 2, SUV4-20H2
2C
(C)
HISTONE H4 PEPTIDEpolymer91274.51UniProt (P62806)MUS MUSCULUS
3D
(A)
S-ADENOSYL-L-HOMOCYSTEINEnon-polymer384.41Chemie (SAH)
4E, F, O
(A, B)
ZINC IONnon-polymer65.43Chemie (ZN)
5G, H, I, J, K...
(A, B)
1,2-ETHANEDIOLnon-polymer62.116Chemie (EDO)
6X, Y, Z
(A, B, C)
waterwater18.0147Chemie (HOH)
Sequence modifications
A, B: 1 - 246 (UniProt: Q6Q783)
PDBExternal DatabaseDetails
Ser 0-expression tag
C: 17 - 25 (UniProt: P62806)
PDBExternal DatabaseDetails
Tyr 25Asn 26conflict
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains3
Total formula weight57598.8
Non-Polymers*Number of molecules20
Total formula weight1573.7
All*Total formula weight59172.5
*Water molecules are not included.

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PDB entries from 2025-06-18

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