4AU7

The structure of the Suv4-20h2 ternary complex with histone H4

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	HISTONE-LYSINE N-METHYLTRANSFERASE SUV420H2	polymer	247	28162.1	2	UniProt (Q6Q783) Pfam (PF00856)	MUS MUSCULUS (HOUSE MOUSE)	SUPPRESSOR OF VARIEGATION 4-20 HOMOLOG 2, SU(VAR)4-20 HOMOLOG 2, SUV4-20H2
2	C (C)	HISTONE H4 PEPTIDE	polymer	9	1274.5	1	UniProt (P62806)	MUS MUSCULUS
3	D (A)	S-ADENOSYL-L-HOMOCYSTEINE	non-polymer		384.4	1	Chemie (SAH) PubChem (16760024) PubChem (193) PubChem (25210495) PubChem (13792) PubChem (177678424) PubChem (44361184) PubChem (21125603) PubChem (46936206) PubChem (50989525) PubChem (25203782) PubChem (51380914) PubChem (52224398) PubChem (189149) PubChem (57544532) PubChem (439155) PubChem (59046843) PubChem (59170628) PubChem (59576228) PubChem (66805708) PubChem (70689219) PubChem (70702054) PubChem (70832431) PubChem (52224400) PubChem (5284331) PubChem (6419189) PubChem (118374891) PubChem (118560068) PubChem (71170554) PubChem (13231890) PubChem (164157219) PubChem (126969526) PubChem (129105892) PubChem (143518505) PubChem (154578335) PubChem (163054214) PubChem (163335525)
4	E, F, O (A, B)	ZINC ION	non-polymer		65.4	3	Chemie (ZN)
5	G, H, I, J, K... (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	16	Chemie (EDO)
6	X, Y, Z (A, B, C)	water	water		18.0	147	Chemie (HOH)

Sequence modifications

A, B: 1 - 246 (UniProt: Q6Q783)

PDB	External Database	Details
Ser 0	-	expression tag

C: 17 - 25 (UniProt: P62806)

PDB	External Database	Details
Tyr 25	Asn 26	conflict

Contents of the asymmetric unit

Polymers	Number of chains	3
	Total formula weight	57598.8
Non-Polymers*	Number of molecules	20
	Total formula weight	1573.7
All*	Total formula weight	59172.5

*Water molecules are not included.