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4ASF

The structure of modified benzoquinone ansamycins bound to yeast N- terminal Hsp90

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
ATP-DEPENDENT MOLECULAR CHAPERONE HSP82polymer22024873.41UniProt (P02829)
Pfam (PF02518)
SACCHAROMYCES CEREVISIAE (BAKER'S YEAST)HSP90,82 KDA HEAT SHOCK PROTEIN, HEAT SHOCK PROTEIN HSP90 HEAT-INDUCIBLE ISOFORM
2B
(A)
(8S,9R,13R,14S,16R)-21-(furan-2-yl)-13-hydroxy-8,14,19-trimethoxy-16-methyl-4,10,12-trimethylidene-3,20,22-trioxo-2-azabicyclo[16.3.1]docosa-1(21),18-dien-9-yl carbamatenon-polymer626.71Chemie (62U)
3C, D, E
(A)
NICKEL (II) IONnon-polymer58.73Chemie (NI)
4F
(A)
waterwater18.082Chemie (HOH)
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight24873.4
Non-Polymers*Number of molecules4
Total formula weight802.8
All*Total formula weight25676.2
*Water molecules are not included.

246704

PDB entries from 2025-12-24

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