4AD6
Synthesis and SAR of guanine based analogues for HPPK inhibitors
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A, B | 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase | polymer | 161 | 18304.1 | 2 | UniProt (A0A0H3JKY1) Pfam (PF01288) In PDB | Staphylococcus aureus | |
2 | A, B | 7-(2-HYDROXYETHYL)-8-MERCAPTOGUANINE | non-polymer | 227.2 | 2 | Chemie (GSY) | |||
3 | water | water | 18.0 | 167 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 158 (UniProt: A0A0H3JKY1)
PDB | External Database | Details |
---|---|---|
Gly -2 | - | expression tag |
Ser -1 | - | expression tag |
His 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 2 |
Total formula weight | 36608.2 | |
Non-Polymers* | Number of molecules | 2 |
Total formula weight | 454.5 | |
All* | Total formula weight | 37062.7 |