4AAP

Crystal structure of JMJD5 domain of human Lysine-specific demethylase 8 (KDM8) in complex with N-oxalylglycine (NOG)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	LYSINE-SPECIFIC DEMETHYLASE 8	polymer	239	27764.5	2	UniProt (Q8N371) Pfam (PF13621)	HOMO SAPIENS (HUMAN)	JMJC DOMAIN-CONTAINING PROTEIN 5, JUMONJI DOMAIN-CONTAINING PROTEIN 5
2	C, E, F, H (A, B)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
3	D, G (A, B)	N-OXALYLGLYCINE	non-polymer		147.1	2	Chemie (OGA)
4	I, J (A, B)	water	water		18.0	29	Chemie (HOH)

Sequence modifications

A, B: 218 - 454 (UniProt: Q8N371)

PDB	External Database	Details
Ser -1	-	expression tag
Met 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55529.0
Non-Polymers*	Number of molecules	6
	Total formula weight	555.8
All*	Total formula weight	56084.8

*Water molecules are not included.