4A9L
N-TERMINAL BROMODOMAIN OF HUMAN BRD4 WITH 1,3-DIMETHYL-6-(MORPHOLINE- 4-SULFONYL)-1,2,3,4-TETRAHYDROQUINAZOLIN-2-ONE
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | BROMODOMAIN-CONTAINING PROTEIN 4 | polymer | 127 | 15099.4 | 1 | UniProt (O60885) Pfam (PF00439) | HOMO SAPIENS (HUMAN) | PROTEIN HUNK1, HUMAN BRD4 |
| 2 | B, C, D (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 3 | Chemie (EDO) | |||
| 3 | E (A) | 1,3-dimethyl-6-(morpholin-4-ylsulfonyl)-3,4-dihydroquinazolin-2(1H)-one | non-polymer | 325.4 | 1 | Chemie (P9L) | |||
| 4 | F, G (A) | NITRATE ION | non-polymer | 62.0 | 2 | Chemie (NO3) | |||
| 5 | H (A) | water | water | 18.0 | 237 | Chemie (HOH) |
Sequence modifications
A: 44 - 168 (UniProt: O60885)
| PDB | External Database | Details |
|---|---|---|
| Ser 42 | - | expression tag |
| Met 43 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 15099.4 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 635.6 | |
| All* | Total formula weight | 15735.0 |
