4A64
Crystal structure of the N-terminal domain of human Cul4B at 2.57A resolution
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | CULLIN-4B | polymer | 354 | 41952.1 | 4 | UniProt (Q13620) Pfam (PF00888) In PDB | HOMO SAPIENS (HUMAN) | CUL4B, CUL-4B |
| 2 | A, B, C, D | 1,2-ETHANEDIOL | non-polymer | 62.1 | 7 | Chemie (EDO) | |||
| 3 | water | water | 18.0 | 253 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 188 - 539 (UniProt: Q13620)
| PDB | External Database | Details |
|---|---|---|
| Ser 186 | - | expression tag |
| Met 187 | - | expression tag |
| Arg 498 | Val 498 | engineered mutation |
| Asp 502 | Leu 502 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 167808.2 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 434.5 | |
| All* | Total formula weight | 168242.7 |
