4A64
Crystal structure of the N-terminal domain of human Cul4B at 2.57A resolution
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| A | 0031625 | molecular_function | ubiquitin protein ligase binding |
| B | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| B | 0031625 | molecular_function | ubiquitin protein ligase binding |
| C | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| C | 0031625 | molecular_function | ubiquitin protein ligase binding |
| D | 0006511 | biological_process | ubiquitin-dependent protein catabolic process |
| D | 0031625 | molecular_function | ubiquitin protein ligase binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1534 |
| Chain | Residue |
| A | ARG243 |
| A | GLU312 |
| A | ALA316 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1535 |
| Chain | Residue |
| A | ILE345 |
| A | ASP346 |
| A | ARG347 |
| B | GLN460 |
| B | SER463 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE EDO A 1536 |
| Chain | Residue |
| A | GLN276 |
| A | SER348 |
| A | ASP272 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO A 1537 |
| Chain | Residue |
| A | GLN210 |
| A | ILE250 |
| A | HIS278 |
| A | GLN281 |
| A | MET282 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 1534 |
| Chain | Residue |
| B | GLN210 |
| B | ILE250 |
| B | HIS278 |
| B | GLN281 |
| B | MET282 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE EDO C 1535 |
| Chain | Residue |
| C | ARG243 |
| C | GLU247 |
| C | ALA316 |
| D | LYS323 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO D 1533 |
| Chain | Residue |
| C | GLN460 |
| D | ILE345 |
| D | ASP346 |
| D | ARG347 |
| D | SER348 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | ASN193 | |
| B | ASN193 | |
| C | ASN193 | |
| D | ASN193 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 8 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:Q13619 |
| Chain | Residue | Details |
| A | LEU190 | |
| B | LEU190 | |
| C | LEU190 | |
| D | LEU190 |
