3ZJY
Crystal Structure of Importin 13 - RanGTP - eIF1A complex
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D, F (A, D, F) | GTP-BINDING NUCLEAR PROTEIN RAN | polymer | 180 | 20594.0 | 3 | UniProt (P62826) Pfam (PF00071) | HOMO SAPIENS (HUMAN) | ANDROGEN RECEPTOR-ASSOCIATED PROTEIN 24, GTPASE RAN, RAS-LIKE PROTEIN TC4, RAS-RELATED NUCLEAR PROTEIN |
| 2 | B, E, G (B, E, G) | IMPORTIN-13 | polymer | 963 | 108293.7 | 3 | UniProt (O94829) Pfam (PF03810) Pfam (PF08389) Pfam (PF18773) Pfam (PF18786) Pfam (PF18806) | HOMO SAPIENS (HUMAN) | IMP13, KARYOPHERIN-13, KAP13, RAN-BINDING PROTEIN 13, RANBP13, IMPORTIN13 |
| 3 | C (C) | EUKARYOTIC TRANSLATION INITIATION FACTOR 1A, X-CHROMOSOMAL | polymer | 112 | 12946.9 | 1 | UniProt (P47813) Pfam (PF01176) | HOMO SAPIENS (HUMAN) | EIF-1A X ISOFORM, EUKARYOTIC TRANSLATION INITIATION FACTOR 4C, EIF-4C, TRANSLATION INITIATION FACTOR 1A |
| 4 | H, J, L (A, D, F) | GUANOSINE-5'-TRIPHOSPHATE | non-polymer | 523.2 | 3 | Chemie (GTP) | |||
| 5 | I, K, M (A, D, F) | MAGNESIUM ION | non-polymer | 24.3 | 3 | Chemie (MG) |
Sequence modifications
A, D, F: 1 - 180 (UniProt: P62826)
| PDB | External Database | Details |
|---|---|---|
| Leu 69 | Gln 69 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 7 |
| Total formula weight | 399610.0 | |
| Non-Polymers* | Number of molecules | 6 |
| Total formula weight | 1642.5 | |
| All* | Total formula weight | 401252.5 |
