3ZHR
Crystal structure of the H747A mutant of the SucA domain of Mycobacterium smegmatis KGD showing the active site lid closed
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | MULTIFUNCTIONAL 2-OXOGLUTARATE METABOLISM ENZYME | polymer | 868 | 97099.6 | 4 | UniProt (A0R2B1) Pfam (PF00676) Pfam (PF02779) Pfam (PF16870) | MYCOBACTERIUM SMEGMATIS | 2-HYDROXY-3-OXOADIPATE SYNTHASE, HOA SYNTHASE, HOAS, 2-OXOGLUTARATE CARBOXY-LYASE, 2-OXOGLUTARATE DECARBOXYLASE, ALPHA-KETOGLUTARATE DECARBOXYLASE, KG DECARBOXYLASE, KGD, ALPHA-KETOGLUTARATE-GLYOXYLATE CARBOLIGASE, 2-OXOGLUTARATE DEHYDROGENASE E1 COMPONENT, ODH E1 COMPONENT, ALPHA-KETOGLUTARATE DEHYDROGENASE E1 COMPONENT, KDH E1 COMPONENT, DIHYDROLIPOYLLYSINE-RESIDUE SUCCINYLTRANSFERASE COMPONENT OF 2-OXOGLUTARATE DEHYDROGENASE COMPLEX, 2-OXOGLUTARATE DEHYDROGENASE COMPLEX E2 COMPONENT, ODH E2 COMPONENT, OGDC-E2, DIHYDROLIPOAMIDE SUCCINYLTRANSFERASE |
| 2 | E, I, M, Q (A, B, C, D) | THIAMINE DIPHOSPHATE | non-polymer | 425.3 | 4 | Chemie (TPP) | |||
| 3 | F, J, N, R (A, B, C, D) | MAGNESIUM ION | non-polymer | 24.3 | 4 | Chemie (MG) | |||
| 4 | G, K, O, S (A, B, C, D) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 5 | H, L, P, T (A, B, C, D) | (4S)-2-METHYL-2,4-PENTANEDIOL | non-polymer | 118.2 | 4 | Chemie (MPD) | |||
| 6 | U, V, W, X (A, B, C, D) | water | water | 18.0 | 1175 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 361 - 1227 (UniProt: A0R2B1)
| PDB | External Database | Details |
|---|---|---|
| Gly 360 | - | expression tag |
| Ala 747 | His 747 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 388398.3 | |
| Non-Polymers* | Number of molecules | 16 |
| Total formula weight | 2431.5 | |
| All* | Total formula weight | 390829.8 |
