3WWQ

Crystal structure of FAAP20 UBZ domain in complex with Lys63-linked diubiquitin

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, D, G, J (A, D, G, J)	Ubiquitin	polymer	76	8604.8	4	UniProt (P0CG50) Pfam (PF00240)	Mus musculus (mouse)
2	B, E, H, K (B, E, H, K)	Ubiquitin	polymer	77	8691.9	4	UniProt (P0CG50) Pfam (PF00240)	Mus musculus (mouse)
3	C, F, I, L (C, F, I, L)	Fanconi anemia-associated protein of 20 kDa	polymer	44	4849.5	4	UniProt (Q6NZ36) Pfam (PF15750)	Homo sapiens (human)
4	M, N, O, P (C, F, I, L)	ZINC ION	non-polymer		65.4	4	Chemie (ZN)
5	AA, BA, Q, R, S... (K, L, A, B, C...)	water	water		18.0	346	Chemie (HOH)

Sequence modifications

A, D, G, J: 1 - 76 (UniProt: P0CG50)

PDB	External Database	Details
Arg 63	Lys 63	engineered mutation

B, E, H, K: 1 - 76 (UniProt: P0CG50)

PDB	External Database	Details
Asp 77	-	SEE REMARK 999

C, F, I, L: 142 - 180 (UniProt: Q6NZ36)

PDB	External Database	Details
Gly 137	-	expression tag
Pro 138	-	expression tag
Gly 139	-	expression tag
His 140	-	expression tag
Met 141	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	88585.1
Non-Polymers*	Number of molecules	4
	Total formula weight	261.6
All*	Total formula weight	88846.7

*Water molecules are not included.