3WWQ

Crystal structure of FAAP20 UBZ domain in complex with Lys63-linked diubiquitin

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0043130	molecular_function	ubiquitin binding
F	0043130	molecular_function	ubiquitin binding
I	0043130	molecular_function	ubiquitin binding
L	0043130	molecular_function	ubiquitin binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN C 201

Chain	Residue
C	CYS147
C	CYS150
C	HIS166
C	CYS170

---

site_id	AC2
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN F 201

Chain	Residue
F	CYS147
F	CYS150
F	HIS166
F	CYS170

---

site_id	AC3
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN I 201

Chain	Residue
I	CYS150
I	HIS166
I	CYS170
I	CYS147

---

site_id	AC4
Number of Residues	4
Details	BINDING SITE FOR RESIDUE ZN L 201

Chain	Residue
L	CYS147
L	CYS150
L	HIS166
L	CYS170

---

Functional Information from PROSITE/UniProt

site_id	PS00299
Number of Residues	26
Details	UBIQUITIN_1 Ubiquitin domain signature. KakIqDkegIPpdqQrLIFaGkqleD

Chain	Residue	Details
A	LYS27-ASP52
B	LYS27-ASP52

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	144
Details	ZN_FING: UBZ2-type => ECO:0000255|PROSITE-ProRule:PRU01254

Chain	Residue	Details
C	LEU144-TRP180
F	LEU144-TRP180
I	LEU144-TRP180
L	LEU144-TRP180
H	ARG54
H	ARG72
K	ARG54
K	ARG72

---

site_id	SWS_FT_FI2
Number of Residues	16
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU01254

Chain	Residue	Details
C	CYS147
I	CYS150
I	HIS166
I	CYS170
L	CYS147
L	CYS150
L	HIS166
L	CYS170
C	CYS150
C	HIS166
C	CYS170
F	CYS147
F	CYS150
F	HIS166
F	CYS170
I	CYS147

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	MOD_RES: Phosphoserine; by PINK1 => ECO:0000250|UniProtKB:P0CG48

Chain	Residue	Details
B	SER65
E	SER65
H	SER65
K	SER65

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: ADP-ribosylglycine => ECO:0000250|UniProtKB:P0CG48

Chain	Residue	Details
B	GLY76
E	GLY76
H	GLY76
K	GLY76

---

site_id	SWS_FT_FI5
Number of Residues	28
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000250|UniProtKB:P0CG48

Chain	Residue	Details
B	LYS6
E	LYS27
E	LYS29
E	LYS33
E	LYS48
E	LYS63
H	LYS6
H	LYS11
H	LYS27
H	LYS29
H	LYS33
B	LYS11
H	LYS48
H	LYS63
K	LYS6
K	LYS11
K	LYS27
K	LYS29
K	LYS33
K	LYS48
K	LYS63
B	LYS27
B	LYS29
B	LYS33
B	LYS48
B	LYS63
E	LYS6
E	LYS11

---

site_id	SWS_FT_FI6
Number of Residues	8
Details	CROSSLNK: Glycyl lysine isopeptide (Gly-Lys) (interchain with K-? in acceptor proteins) => ECO:0000255|PROSITE-ProRule:PRU00214

Chain	Residue	Details
B	GLY76
E	GLY76
H	GLY76
K	GLY76

---