3WPN

Kinesin spindle protein Eg5 in complex with ATP-competitive inhibitor PVZB1194

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (A)	Kinesin-like protein KIF11	polymer	382	42875.6	1	UniProt (P52732) Pfam (PF00225)	Homo sapiens (human)	Kinesin spindle protein Eg5
2	B (A)	3'-fluoro-4'-(trifluoromethyl)biphenyl-4-sulfonamide	non-polymer		319.3	1	Chemie (B4S)
3	C (A)	water	water		18.0	8	Chemie (HOH)

Sequence modifications

A: 1 - 369 (UniProt: P52732)

PDB	External Database	Details
Met -5	-	expression tag
Asn -4	-	expression tag
His -3	-	expression tag
Lys -2	-	expression tag
Val -1	-	expression tag
His 0	-	expression tag
Gln 370	-	expression tag
His 371	-	expression tag
His 372	-	expression tag
His 373	-	expression tag
His 374	-	expression tag
His 375	-	expression tag
His 376	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	1
	Total formula weight	42875.6
Non-Polymers*	Number of molecules	1
	Total formula weight	319.3
All*	Total formula weight	43194.9

*Water molecules are not included.