3WIH
Crystal structure of the third fibronectin domain (Fn3) of human ROBO1 in complex with the Fab fragment of murine monoclonal antibody B2212A.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, D (A, B) | Roundabout homolog 1 | polymer | 97 | 10356.5 | 2 | UniProt (Q9Y6N7) Pfam (PF00041) | Homo sapiens (human) | Deleted in U twenty twenty, H-Robo-1 |
| 2 | B, E (L, M) | anti-human ROBO1 antibody B2212A Fab light chain | polymer | 213 | 23571.0 | 2 | Mus musculus | ||
| 3 | C, F (H, I) | anti-human ROBO1 antibody B2212A Fab heavy chain | polymer | 219 | 23732.4 | 2 | Mus musculus | ||
| 4 | G, H (H, I) | GLYCEROL | non-polymer | 92.1 | 2 | Chemie (GOL) | |||
| 5 | I, J, K, L, M... (A, L, H, B, M...) | water | water | 18.0 | 1093 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 115319.9 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 184.2 | |
| All* | Total formula weight | 115504.1 |
