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3VP4

Crystal structure of human glutaminase in complex with inhibitor 4

Entity
Entity IDChain IDDescriptionTypeChain lengthFormula weightNumber of moleculesDB Name (Accession)Biological sourceDescriptive keywords
1A
(A)
Glutaminase kidney isoform, mitochondrialpolymer31634816.71UniProt (O94925)
Pfam (PF04960)
Homo sapiens (human)GLS, K-glutaminase, L-glutamine amidohydrolase
2B
(A)
5,5'-butane-1,4-diylbis(1,3,4-thiadiazol-2-amine)non-polymer256.41Chemie (BP9)
3C
(A)
waterwater18.087Chemie (HOH)
Sequence modifications
A: 221 - 533 (UniProt: O94925)
PDBExternal DatabaseDetails
Gln 218-expression tag
Ser 219-expression tag
Met 220-expression tag
Sequence viewer
Contents of the asymmetric unit
PolymersNumber of chains1
Total formula weight34816.7
Non-Polymers*Number of molecules1
Total formula weight256.4
All*Total formula weight35073.1
*Water molecules are not included.

246031

PDB entries from 2025-12-10

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