3VJO
Crystal structure of the wild-type EGFR kinase domain in complex with AMPPNP.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Epidermal growth factor receptor | polymer | 334 | 37977.9 | 1 | UniProt (P00533) Pfam (PF07714) | Homo sapiens (human) | |
| 2 | B (A) | PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | non-polymer | 506.2 | 1 | Chemie (ANP) | |||
| 3 | C (A) | water | water | 18.0 | 9 | Chemie (HOH) |
Sequence modifications
A: 695 - 1022 (UniProt: P00533)
| PDB | External Database | Details |
|---|---|---|
| Gly 689 | - | expression tag |
| Ala 690 | - | expression tag |
| Met 691 | - | expression tag |
| Gly 692 | - | expression tag |
| Ile 693 | - | expression tag |
| Arg 694 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 37977.9 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 506.2 | |
| All* | Total formula weight | 38484.1 |
