3V9P

Crystal structure of Thymidylate kinase from Burkholderia thailandensis

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Thymidylate kinase	polymer	227	25405.9	2	UniProt (Q2SWM4) Pfam (PF02223)	Burkholderia thailandensis	dTMP kinase
2	C, G (A, B)	(4R)-2-METHYLPENTANE-2,4-DIOL	non-polymer		118.2	2	Chemie (MRD)
3	D, E (A)	GLYCEROL	non-polymer		92.1	2	Chemie (GOL)
4	F, H (A, B)	ACETATE ION	non-polymer		59.0	2	Chemie (ACT)
5	I (B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	1	Chemie (PEG)
6	J, K (A, B)	water	water		18.0	260	Chemie (HOH)

Sequence modifications

A, B: 1 - 206 (UniProt: Q2SWM4)

PDB	External Database	Details
Met -20	-	initiating methionine
Ala -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
His -16	-	expression tag
His -15	-	expression tag
His -14	-	expression tag
His -13	-	expression tag
Met -12	-	expression tag
Gly -11	-	expression tag
Thr -10	-	expression tag
Leu -9	-	expression tag
Glu -8	-	expression tag
Ala -7	-	expression tag
Gln -6	-	expression tag
Thr -5	-	expression tag
Gln -4	-	expression tag
Gly -3	-	expression tag
Pro -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	50811.8
Non-Polymers*	Number of molecules	7
	Total formula weight	644.7
All*	Total formula weight	51456.5

*Water molecules are not included.