3V9P
Crystal structure of Thymidylate kinase from Burkholderia thailandensis
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004798 | molecular_function | thymidylate kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006227 | biological_process | dUDP biosynthetic process |
| A | 0006233 | biological_process | dTDP biosynthetic process |
| A | 0006235 | biological_process | dTTP biosynthetic process |
| A | 0009165 | biological_process | nucleotide biosynthetic process |
| A | 0016301 | molecular_function | kinase activity |
| A | 0016310 | biological_process | phosphorylation |
| A | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
| B | 0004798 | molecular_function | thymidylate kinase activity |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006227 | biological_process | dUDP biosynthetic process |
| B | 0006233 | biological_process | dTDP biosynthetic process |
| B | 0006235 | biological_process | dTTP biosynthetic process |
| B | 0009165 | biological_process | nucleotide biosynthetic process |
| B | 0016301 | molecular_function | kinase activity |
| B | 0016310 | biological_process | phosphorylation |
| B | 0046940 | biological_process | nucleoside monophosphate phosphorylation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MRD A 250 |
| Chain | Residue |
| A | MET72 |
| A | ARG76 |
| A | THR103 |
| A | TYR106 |
| A | GLN107 |
| A | HOH280 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE GOL A 252 |
| Chain | Residue |
| A | HOH329 |
| B | ALA170 |
| B | ARG174 |
| B | GLN177 |
| A | PHE183 |
| A | ILE185 |
| A | HOH208 |
| site_id | AC3 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE GOL A 253 |
| Chain | Residue |
| A | GLU190 |
| A | PRO191 |
| A | ILE192 |
| A | HOH297 |
| B | ALA81 |
| B | LEU82 |
| B | PRO86 |
| B | HOH232 |
| B | HOH284 |
| site_id | AC4 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ACT A 255 |
| Chain | Residue |
| A | GLU44 |
| A | PRO45 |
| A | GLY46 |
| A | GLY47 |
| A | GLY51 |
| A | GLY75 |
| A | ARG76 |
| A | HOH216 |
| A | HOH237 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE MRD B 250 |
| Chain | Residue |
| B | MET72 |
| B | ARG76 |
| B | THR103 |
| B | TYR106 |
| B | GLN107 |
| B | HOH305 |
| site_id | AC6 |
| Number of Residues | 9 |
| Details | BINDING SITE FOR RESIDUE ACT B 255 |
| Chain | Residue |
| B | GLU44 |
| B | PRO45 |
| B | GLY46 |
| B | GLY47 |
| B | GLY51 |
| B | GLY75 |
| B | ARG76 |
| B | HOH227 |
| B | HOH291 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG B 207 |
| Chain | Residue |
| A | PRO180 |
| B | ALA166 |
| B | ARG169 |
| B | ALA170 |
| B | HOH319 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000255|HAMAP-Rule:MF_00165 |
| Chain | Residue | Details |
| A | GLY11 | |
| B | GLY11 |
