3V4N
The Biochemical and Structural Basis for Inhibition of Enterococcus faecalis HMG-CoA Synthatse, mvaS, by Hymeglusin
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | HMG-CoA synthase | polymer | 388 | 42625.9 | 4 | UniProt (Q9FD71) Pfam (PF01154) Pfam (PF08540) | Enterococcus faecalis | |
| 2 | E (B) | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL | non-polymer | 209.2 | 1 | Chemie (BTB) | |||
| 3 | F, G, H, I (A, B, C, D) | water | water | 18.0 | 1494 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 1 - 383 (UniProt: Q9FD71)
| PDB | External Database | Details |
|---|---|---|
| Gly -4 | - | expression tag |
| Ser -3 | - | expression tag |
| Thr -2 | - | expression tag |
| Gly -1 | - | expression tag |
| Ser 0 | - | expression tag |
| Ser 163 | Ala 163 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 170503.7 | |
| Non-Polymers* | Number of molecules | 1 |
| Total formula weight | 209.2 | |
| All* | Total formula weight | 170713.0 |
