3V2A

VEGFR-2/VEGF-A COMPLEX STRUCTURE

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A (R)	Vascular endothelial growth factor receptor 2	polymer	772	86566.5	1	UniProt (P35968) Pfam (PF22854) Pfam (PF21339) Pfam (PF00047) Pfam (PF07679) Pfam (PF22971) Pfam (PF13895)	Homo sapiens (human)	VEGFR-2, Fetal liver kinase 1, FLK-1, Kinase insert domain receptor, KDR, Protein-tyrosine kinase receptor flk-1
2	B (A)	Vascular endothelial growth factor A	polymer	134	15542.6	1	UniProt (P15692) Pfam (PF00341)	Homo sapiens (human)	VEGF-A, Vascular permeability factor, VPF

Sequence modifications

R: 1 - 764 (UniProt: P35968)

PDB	External Database	Details
Arg 765	-	expression tag
Thr 766	-	expression tag
His 767	-	expression tag
His 768	-	expression tag
His 769	-	expression tag
His 770	-	expression tag
His 771	-	expression tag
His 772	-	expression tag

A: 1 - 114 (UniProt: P15692)

PDB	External Database	Details
Ala -12	-	expression tag
Glu -11	-	expression tag
Phe -10	-	expression tag
Gly -9	-	expression tag
Ser -8	-	expression tag
His -7	-	expression tag
His -6	-	expression tag
His -5	-	expression tag
His -4	-	expression tag
His -3	-	expression tag
His -2	-	expression tag
Gly -1	-	expression tag
Ser 0	-	expression tag
Asn 115	-	expression tag
Cys 116	-	expression tag
Asp 117	-	expression tag
Lys 118	-	expression tag
Pro 119	-	expression tag
Arg 120	-	expression tag
Arg 121	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	102109.1
All*	Total formula weight	102109.1

*Water molecules are not included.