3V1G
Forestalling insulin fibrillation by insertion of a chiral clamp mechanism-based application of protein engineering to global health
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C | Insulin | polymer | 21 | 2383.7 | 2 | UniProt (P01308) In PDB | Homo sapiens | |
| 2 | B, D | Insulin | polymer | 30 | 3434.0 | 2 | UniProt (P01308) Pfam (PF00049) In PDB | Homo sapiens | |
| 3 | B, D | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | C | PHENOL | non-polymer | 94.1 | 1 | Chemie (IPH) | |||
| 5 | D | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 6 | water | water | 18.0 | 81 | Chemie (HOH) |
Sequence modifications
B, D: 1 - 30 (UniProt: P01308)
| PDB | External Database | Details |
|---|---|---|
| Dgl 21 | Glu 45 | engineered mutation |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 11635.3 | |
| Non-Polymers* | Number of molecules | 4 |
| Total formula weight | 260.4 | |
| All* | Total formula weight | 11895.7 |
