3UX9
Structural insights into a human anti-IFN antibody exerting therapeutic potential for systemic lupus erythematosus
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, C (A, C) | Interferon alpha-1/13 | polymer | 169 | 19681.4 | 2 | UniProt (P01562) Pfam (PF00143) UniProt (by SIFTS) (A0A087WWS6) | Homo sapiens (human) | interferon 1b, IFN-alpha-1/13, Interferon alpha-D, LeIF D |
| 2 | B, D (B, D) | ScFv antibody | polymer | 256 | 27316.0 | 2 | Homo sapiens (human) | ||
| 3 | E, F, G, H (A, B, C, D) | water | water | 18.0 | 40 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 166 (UniProt: P01562)
| PDB | External Database | Details |
|---|---|---|
| Ser -2 | - | expression tag |
| Asn -1 | - | expression tag |
| Ala 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 93994.7 | |
| All* | Total formula weight | 93994.7 |
