3UWQ

1.80 Angstrom resolution crystal structure of orotidine 5'-phosphate decarboxylase from Vibrio cholerae O1 biovar eltor str. N16961 in complex with uridine-5'-monophosphate (UMP)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	Orotidine 5'-phosphate decarboxylase	polymer	255	27776.8	2	UniProt (Q9KQT7) Pfam (PF00215)	Vibrio cholerae	OMP decarboxylase, OMPDCase, OMPdecase
2	C, I (A, B)	URIDINE-5'-MONOPHOSPHATE	non-polymer		324.2	2	Chemie (U5P)
3	D (A)	3,6,9,12,15,18,21,24,27-NONAOXANONACOSANE-1,29-DIOL	non-polymer		458.5	1	Chemie (XPE)
4	E, F, J, K (A, B)	DI(HYDROXYETHYL)ETHER	non-polymer		106.1	4	Chemie (PEG)
5	G, L (A, B)	TRIETHYLENE GLYCOL	non-polymer		150.2	2	Chemie (PGE)
6	H (A)	2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL	non-polymer		122.1	1	Chemie (TRS)
7	M, N (A, B)	water	water		18.0	468	Chemie (HOH)

Sequence modifications

A, B: 1 - 231 (UniProt: Q9KQT7)

PDB	External Database	Details
Met -23	-	expression tag
His -22	-	expression tag
His -21	-	expression tag
His -20	-	expression tag
His -19	-	expression tag
His -18	-	expression tag
His -17	-	expression tag
Ser -16	-	expression tag
Ser -15	-	expression tag
Gly -14	-	expression tag
Val -13	-	expression tag
Asp -12	-	expression tag
Leu -11	-	expression tag
Gly -10	-	expression tag
Thr -9	-	expression tag
Glu -8	-	expression tag
Asn -7	-	expression tag
Leu -6	-	expression tag
Tyr -5	-	expression tag
Phe -4	-	expression tag
Gln -3	-	expression tag
Ser -2	-	expression tag
Asn -1	-	expression tag
Ala 0	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	55553.6
Non-Polymers*	Number of molecules	10
	Total formula weight	1953.9
All*	Total formula weight	57507.5

*Water molecules are not included.