Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| A | 0005829 | cellular_component | cytosol |
| A | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| A | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
| B | 0004590 | molecular_function | orotidine-5'-phosphate decarboxylase activity |
| B | 0005829 | cellular_component | cytosol |
| B | 0006207 | biological_process | 'de novo' pyrimidine nucleobase biosynthetic process |
| B | 0006221 | biological_process | pyrimidine nucleotide biosynthetic process |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0044205 | biological_process | 'de novo' UMP biosynthetic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | BINDING SITE FOR RESIDUE U5P A 232 |
| Chain | Residue |
| A | ALA9 |
| A | GLY210 |
| A | ARG211 |
| A | PGE236 |
| A | HOH267 |
| A | HOH277 |
| A | HOH288 |
| A | HOH296 |
| A | HOH302 |
| A | HOH331 |
| B | ILE66 |
| A | ASP11 |
| B | HOH249 |
| A | LYS33 |
| A | THR120 |
| A | PRO178 |
| A | GLY179 |
| A | ARG181 |
| A | VAL208 |
| A | ILE209 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | BINDING SITE FOR RESIDUE XPE A 233 |
| Chain | Residue |
| A | ILE66 |
| A | ASN68 |
| A | SER71 |
| A | LYS72 |
| A | HOH346 |
| A | HOH397 |
| A | HOH439 |
| A | HOH478 |
| A | HOH483 |
| B | TYR12 |
| B | ARG211 |
| B | THR214 |
| B | HOH304 |
| B | HOH465 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE PEG A 234 |
| Chain | Residue |
| A | ASP11 |
| A | GLN215 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE PEG A 235 |
| Chain | Residue |
| A | HIS51 |
| A | PHE55 |
| A | GLY81 |
| A | ARG171 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PGE A 236 |
| Chain | Residue |
| A | ARG211 |
| A | U5P232 |
| A | HOH433 |
| A | HOH444 |
| B | ILE66 |
| B | ASN68 |
| site_id | AC6 |
| Number of Residues | 12 |
| Details | BINDING SITE FOR RESIDUE TRS A 237 |
| Chain | Residue |
| A | ASP23 |
| A | ILE25 |
| A | ASP26 |
| A | PRO27 |
| A | LEU112 |
| A | ASP153 |
| A | LYS174 |
| A | GLU220 |
| A | HOH335 |
| A | HOH370 |
| A | HOH461 |
| A | HOH471 |
| site_id | AC7 |
| Number of Residues | 19 |
| Details | BINDING SITE FOR RESIDUE U5P B 232 |
| Chain | Residue |
| A | ILE66 |
| A | HOH290 |
| A | HOH430 |
| B | ALA9 |
| B | ASP11 |
| B | LYS33 |
| B | THR120 |
| B | PRO178 |
| B | ARG181 |
| B | VAL208 |
| B | GLY210 |
| B | ARG211 |
| B | HOH266 |
| B | HOH320 |
| B | HOH376 |
| B | HOH381 |
| B | HOH397 |
| B | HOH429 |
| B | HOH433 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PEG B 233 |
| Chain | Residue |
| B | HIS51 |
| B | GLY54 |
| B | PHE55 |
| B | GLY81 |
| B | HOH313 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE PEG B 234 |
| Chain | Residue |
| A | ALA201 |
| A | SER202 |
| A | HOH448 |
| B | SER163 |
| B | HOH399 |
| B | HOH406 |
| site_id | BC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE PGE B 235 |
| Chain | Residue |
| B | ALA78 |
| B | GLU79 |
| B | PRO105 |
Functional Information from PROSITE/UniProt
| site_id | PS00156 |
| Number of Residues | 14 |
| Details | OMPDECASE Orotidine 5'-phosphate decarboxylase active site. VFlDlKfhDIPnTC |
| Chain | Residue | Details |
| A | VAL57-CYS70 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | LYS62 | |
| B | LYS62 | |
| Chain | Residue | Details |
| A | ASP11 | |
| B | LYS33 | |
| B | ASP60 | |
| B | THR120 | |
| B | ARG181 | |
| B | GLN190 | |
| B | GLY210 | |
| B | ARG211 | |
| A | LYS33 | |
| A | ASP60 | |
| A | THR120 | |
| A | ARG181 | |
| A | GLN190 | |
| A | GLY210 | |
| A | ARG211 | |
| B | ASP11 | |
