3UWP
Crystal structure of Dot1l in complex with 5-iodotubercidin
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Histone-lysine N-methyltransferase, H3 lysine-79 specific | polymer | 438 | 50124.0 | 1 | UniProt (Q8TEK3) Pfam (PF08123) In PDB | Homo sapiens (human) | DOT1-like protein, Histone H3-K79 methyltransferase, H3-K79-HMTase, Lysine N-methyltransferase 4 |
2 | A | (2R,3R,4S,5R)-2-(4-AMINO-5-IODO-7H-PYRROLO[2,3-D]PYRIMIDIN-7-YL)-5-(HYDROXYMETHYL)TETRAHYDROFURAN-3,4-DIOL | non-polymer | 392.1 | 1 | Chemie (5ID) | |||
3 | A | IODIDE ION | non-polymer | 126.9 | 2 | Chemie (IOD) | |||
4 | A | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
5 | A | UNKNOWN ATOM OR ION | non-polymer | 6 | Chemie (UNX) | ||||
6 | water | water | 18.0 | 66 | Chemie (HOH) |
Sequence modifications
A: 1 - 420 (UniProt: Q8TEK3)
PDB | External Database | Details |
---|---|---|
Met -17 | - | expression tag |
His -16 | - | expression tag |
His -15 | - | expression tag |
His -14 | - | expression tag |
His -13 | - | expression tag |
His -12 | - | expression tag |
His -11 | - | expression tag |
Ser -10 | - | expression tag |
Ser -9 | - | expression tag |
Gly -8 | - | expression tag |
Arg -7 | - | expression tag |
Glu -6 | - | expression tag |
Asn -5 | - | expression tag |
Leu -4 | - | expression tag |
Tyr -3 | - | expression tag |
Phe -2 | - | expression tag |
Gln -1 | - | expression tag |
Gly 0 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 50124.0 | |
Non-Polymers* | Number of molecules | 10 |
Total formula weight | 668.9 | |
All* | Total formula weight | 50793.0 |