3UWP
Crystal structure of Dot1l in complex with 5-iodotubercidin
Functional Information from GO Data
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 10 |
| Details | BINDING SITE FOR RESIDUE 5ID A 421 |
| Chain | Residue |
| A | TYR58 |
| A | IOD422 |
| A | GLU129 |
| A | GLY163 |
| A | GLU186 |
| A | LYS187 |
| A | GLY221 |
| A | ASP222 |
| A | PHE223 |
| A | ASN241 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE IOD A 422 |
| Chain | Residue |
| A | 5ID421 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE IOD A 423 |
| Chain | Residue |
| A | GLY246 |
| A | VAL249 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | BINDING SITE FOR RESIDUE NA A 424 |
| Chain | Residue |
| A | LYS52 |
| A | LEU53 |
| A | MET55 |
| A | ASN57 |
| A | HOH480 |
| A | HOH481 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | TYR136 | |
| A | PHE159 | |
| A | GLU186 | |
| A | ASP222 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER297 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
| Chain | Residue | Details |
| A | SER374 |
