3UWP
Crystal structure of Dot1l in complex with 5-iodotubercidin
Functional Information from GO Data
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 10 |
Details | BINDING SITE FOR RESIDUE 5ID A 421 |
Chain | Residue |
A | TYR58 |
A | IOD422 |
A | GLU129 |
A | GLY163 |
A | GLU186 |
A | LYS187 |
A | GLY221 |
A | ASP222 |
A | PHE223 |
A | ASN241 |
site_id | AC2 |
Number of Residues | 1 |
Details | BINDING SITE FOR RESIDUE IOD A 422 |
Chain | Residue |
A | 5ID421 |
site_id | AC3 |
Number of Residues | 2 |
Details | BINDING SITE FOR RESIDUE IOD A 423 |
Chain | Residue |
A | GLY246 |
A | VAL249 |
site_id | AC4 |
Number of Residues | 6 |
Details | BINDING SITE FOR RESIDUE NA A 424 |
Chain | Residue |
A | LYS52 |
A | LEU53 |
A | MET55 |
A | ASN57 |
A | HOH480 |
A | HOH481 |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | BINDING: |
Chain | Residue | Details |
A | TYR136 | |
A | PHE159 | |
A | GLU186 | |
A | ASP222 |
site_id | SWS_FT_FI2 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
A | SER297 |
site_id | SWS_FT_FI3 |
Number of Residues | 1 |
Details | MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:19690332, ECO:0007744|PubMed:20068231, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163 |
Chain | Residue | Details |
A | SER374 |