3UWL

Crystal structure of Enteroccocus faecalis thymidylate synthase (EfTS) in complex with 5-formyl tetrahydrofolate

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, C (A, C)	Thymidylate synthase	polymer	315	36386.0	2	UniProt (Q834R3) Pfam (PF00303)	Enterococcus faecalis	TS, TSase
2	B, D (B, D)	Thymidylate synthase	polymer	315	36462.1	2	UniProt (Q834R3) Pfam (PF00303)	Enterococcus faecalis	TS, TSase
3	E, F, H, O, P... (B, C, D)	SULFATE ION	non-polymer		96.1	6	Chemie (SO4)
4	G, Q (B, D)	N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid	non-polymer		473.4	2	Chemie (FFO)
5	I, J, K, L, M... (B, C, D)	1,2-ETHANEDIOL	non-polymer		62.1	8	Chemie (EDO)
6	U, V, W, X (A, B, C, D)	water	water		18.0	799	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	145696.1
Non-Polymers*	Number of molecules	16
	Total formula weight	2019.8
All*	Total formula weight	147715.9

*Water molecules are not included.