3UV4

Crystal Structure of the second bromodomain of human Transcription initiation factor TFIID subunit 1 (TAF1)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (A, B)	second bromodomain of human Transcription initiation factor TFIID subunit 1 (TAF1)	polymer	158	18354.5	2	UniProt (P21675) Pfam (PF00439)	Homo sapiens (human)	Cell cycle gene 1 protein, TBP-associated factor 250 kDa, p250, Transcription initiation factor TFIID 250 kDa subunit, TAF(II)250, TAFII-250, TAFII250
2	C, E, F (A, B)	1,2-ETHANEDIOL	non-polymer		62.1	3	Chemie (EDO)
3	D (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	G (B)	PHOSPHATE ION	non-polymer		95.0	1	Chemie (PO4)
5	H, I (A, B)	water	water		18.0	305	Chemie (HOH)

Sequence modifications

A, B: 1522 - 1656 (UniProt: P21675)

PDB	External Database	Details
Met 1499	-	expression tag
His 1500	-	expression tag
His 1501	-	expression tag
His 1502	-	expression tag
His 1503	-	expression tag
His 1504	-	expression tag
His 1505	-	expression tag
Ser 1506	-	expression tag
Ser 1507	-	expression tag
Gly 1508	-	expression tag
Val 1509	-	expression tag
Asp 1510	-	expression tag
Leu 1511	-	expression tag
Gly 1512	-	expression tag
Thr 1513	-	expression tag
Glu 1514	-	expression tag
Asn 1515	-	expression tag
Leu 1516	-	expression tag
Tyr 1517	-	expression tag
Phe 1518	-	expression tag
Gln 1519	-	expression tag
Ser 1520	-	expression tag
Met 1521	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	2
	Total formula weight	36709.0
Non-Polymers*	Number of molecules	5
	Total formula weight	373.3
All*	Total formula weight	37082.2

*Water molecules are not included.