3UV4
Crystal Structure of the second bromodomain of human Transcription initiation factor TFIID subunit 1 (TAF1)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004402 | molecular_function | histone acetyltransferase activity |
| A | 0005669 | cellular_component | transcription factor TFIID complex |
| A | 0006366 | biological_process | transcription by RNA polymerase II |
| A | 0016251 | molecular_function | RNA polymerase II general transcription initiation factor activity |
| A | 0017025 | molecular_function | TBP-class protein binding |
| B | 0004402 | molecular_function | histone acetyltransferase activity |
| B | 0005669 | cellular_component | transcription factor TFIID complex |
| B | 0006366 | biological_process | transcription by RNA polymerase II |
| B | 0016251 | molecular_function | RNA polymerase II general transcription initiation factor activity |
| B | 0017025 | molecular_function | TBP-class protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | BINDING SITE FOR RESIDUE EDO A 2 |
| Chain | Residue |
| A | HOH22 |
| A | HOH56 |
| A | HOH263 |
| A | HOH284 |
| A | PHE1530 |
| A | PRO1548 |
| A | ASN1604 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE GOL A 1 |
| Chain | Residue |
| A | HOH264 |
| A | HOH276 |
| A | ARG1575 |
| A | SER1608 |
| A | GLN1609 |
| A | TYR1610 |
| A | HOH200 |
| A | HOH261 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | BINDING SITE FOR RESIDUE EDO B 1 |
| Chain | Residue |
| B | HOH83 |
| B | HOH246 |
| B | HOH302 |
| B | HOH303 |
| B | PHE1530 |
| B | PRO1548 |
| B | PHE1549 |
| B | ASN1604 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE EDO B 3 |
| Chain | Residue |
| B | HOH142 |
| B | HOH248 |
| B | VAL1526 |
| B | GLN1609 |
| B | TYR1610 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | BINDING SITE FOR RESIDUE PO4 B 1657 |
| Chain | Residue |
| B | HOH11 |
| B | HOH32 |
| B | HOH247 |
| B | ARG1575 |
| B | SER1608 |
Functional Information from PROSITE/UniProt
| site_id | PS00633 |
| Number of Residues | 58 |
| Details | BROMODOMAIN_1 Bromodomain signature. SwpFhhpvNkkfvp..DYYkvIvnpMdletIrkniskhk..Yqsresflddvnl.IlaNSvkY |
| Chain | Residue | Details |
| A | SER1546-TYR1603 |
