3UQ0
Crystal structure of the post-catalytic product complex of polymerase lambda with an rAMP at the primer terminus.
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | DNA polymerase lambda | polymer | 329 | 36736.0 | 1 | UniProt (Q9UGP5) Pfam (PF14716) Pfam (PF10391) Pfam (PF14792) Pfam (PF14791) | Homo sapiens (human) | Pol Lambda, DNA polymerase beta-2, Pol beta2, DNA polymerase kappa |
| 2 | B (T) | 5'-D(*CP*GP*GP*CP*TP*GP*TP*AP*CP*TP*G)-3' | polymer | 11 | 3365.2 | 1 | |||
| 3 | C (P) | 5'-D(*CP*AP*GP*TP*AP*CP)-R(P*A)-3' | polymer | 7 | 2122.4 | 1 | |||
| 4 | D (D) | 5'-D(P*GP*CP*CP*G)-3' | polymer | 4 | 1191.8 | 1 | |||
| 5 | E (A) | SODIUM ION | non-polymer | 23.0 | 1 | Chemie (NA) | |||
| 6 | F, G, H (A) | SULFATE ION | non-polymer | 96.1 | 3 | Chemie (SO4) | |||
| 7 | I, J (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 8 | K, L (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 9 | M, N, O, P (A, T, P, D) | water | water | 18.0 | 289 | Chemie (HOH) |
Sequence modifications
A: 242 - 575 (UniProt: Q9UGP5)
| PDB | External Database | Details |
|---|---|---|
| Lys 463 | Ser 463 | SEE REMARK 999 |
| Gly 464 | Gln 464 | SEE REMARK 999 |
| Glu 470 | Gln 470 | SEE REMARK 999 |
| Thr 471 | Gln 471 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 43415.5 | |
| Non-Polymers* | Number of molecules | 8 |
| Total formula weight | 506.2 | |
| All* | Total formula weight | 43921.7 |
