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3UQ0

Crystal structure of the post-catalytic product complex of polymerase lambda with an rAMP at the primer terminus.

Functional Information from GO Data
ChainGOidnamespacecontents
A0003677molecular_functionDNA binding
A0003887molecular_functionDNA-directed DNA polymerase activity
A0006281biological_processDNA repair
A0016779molecular_functionnucleotidyltransferase activity
A0034061molecular_functionDNA polymerase activity
Functional Information from PDB Data
site_idAC1
Number of Residues5
DetailsBINDING SITE FOR RESIDUE NA A 1
ChainResidue
ASER339
AILE341
AALA344
PDA5
PHOH122

site_idAC2
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 2
ChainResidue
AASP427
AHOH237
AARG386
ASER417
AGLY426

site_idAC3
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 3
ChainResidue
AGLY442
APHE444
ASER445
AHOH608
AHOH609

site_idAC4
Number of Residues5
DetailsBINDING SITE FOR RESIDUE SO4 A 4
ChainResidue
AHIS440
AARG441
APRO495
AHOH595
AHOH632

site_idAC5
Number of Residues2
DetailsBINDING SITE FOR RESIDUE EDO A 7
ChainResidue
ALYS347
AARG478

site_idAC6
Number of Residues1
DetailsBINDING SITE FOR RESIDUE EDO A 8
ChainResidue
AARG364

Functional Information from PROSITE/UniProt
site_idPS00522
Number of Residues20
DetailsDNA_POLYMERASE_X DNA polymerase family X signature. GSYrRGkatCgDVDVLIthP
ChainResidueDetails
AGLY416-PRO435

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues1
DetailsACT_SITE: Schiff-base intermediate with DNA => ECO:0000269|PubMed:11457865
ChainResidueDetails
ALYS312

site_idSWS_FT_FI2
Number of Residues4
DetailsBINDING: BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFP, ECO:0007744|PDB:2PFQ
ChainResidueDetails
AARG386
ASER417
AGLY426
AALA518

site_idSWS_FT_FI3
Number of Residues3
DetailsBINDING: BINDING => ECO:0000269|PubMed:17475573, ECO:0007744|PDB:2PFO, ECO:0007744|PDB:2PFQ
ChainResidueDetails
AASP427
AASP429
APRO495

227344

PDB entries from 2024-11-13

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