3UP0

Nuclear receptor DAF-12 from hookworm Ancylostoma ceylanicum in complex with (25S)-delta7-dafachronic acid

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B	aceDAF-12	polymer	243	27770.7	2	Pfam (PF00104) UniProt (by SIFTS) (H0USY8) In PDB	Ancylostoma ceylanicum
2	P, Q	Nuclear receptor coactivator 2	polymer	14	1708.9	2	UniProt (Q15596) In PDB	Homo sapiens	SRC2, steroid receptor coactivator-2, NCoA-2, Class E basic helix-loop-helix protein 75, bHLHe75, Transcriptional intermediary factor 2, hTIF2
3	A, B	(5beta,14beta,17alpha,25S)-3-oxocholest-7-en-26-oic acid	non-polymer		414.6	2	Chemie (D7S)
4		water	water		18.0	534	Chemie (HOH)

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	58959.3
Non-Polymers*	Number of molecules	2
	Total formula weight	829.2
All*	Total formula weight	59788.6

*Water molecules are not included.