3UOA

Crystal structure of the MALT1 paracaspase (P21 form)

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B (B, C)	Mucosa-associated lymphoid tissue lymphoma translocation protein 1	polymer	390	44432.1	2	UniProt (Q9UDY8) Pfam (PF00656) Pfam (PF18703)	Homo sapiens	MALT lymphoma-associated translocation, Paracaspase
2	C, D (L, M)	Z-Val-Arg-Pro-DL-Arg-fluoromethylketone	polymer	6	697.2	2	BIRD (PRD_001076)		MALT1 Inhibitor, Z-VRPR-FMK
3	E, F (C)	MAGNESIUM ION	non-polymer		24.3	2	Chemie (MG)
4	G, H, I, J (B, C, L, M)	water	water		18.0	357	Chemie (HOH)

Sequence modifications

B, C: 339 - 719 (UniProt: Q9UDY8)

PDB	External Database	Details
Met 338	-	expression tag
Leu 720	-	expression tag
Glu 721	-	expression tag
His 722	-	expression tag
His 723	-	expression tag
His 724	-	expression tag
His 725	-	expression tag
His 726	-	expression tag
His 727	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	90258.7
Non-Polymers*	Number of molecules	2
	Total formula weight	48.6
All*	Total formula weight	90307.3

*Water molecules are not included.