Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004197 | molecular_function | cysteine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE MG C 1 |
| Chain | Residue |
| C | GLU388 |
| C | GLU437 |
| site_id | AC2 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE MG C 2 |
| site_id | AC3 |
| Number of Residues | 16 |
| Details | BINDING SITE FOR CHAIN L OF Z-VAL-ARG-PRO-DL-ARG-FLUOROMETHYLKETONE |
| Chain | Residue |
| B | HIS415 |
| B | GLY416 |
| B | ASP462 |
| B | CYS464 |
| B | GLU497 |
| B | ALA498 |
| B | PHE499 |
| B | GLU500 |
| B | ILE501 |
| B | GLN502 |
| B | LEU359 |
| B | ALA361 |
| B | PRO362 |
| B | ASP365 |
| B | ALA413 |
| B | GLY414 |
| site_id | AC4 |
| Number of Residues | 15 |
| Details | BINDING SITE FOR CHAIN M OF Z-VAL-ARG-PRO-DL-ARG-FLUOROMETHYLKETONE |
| Chain | Residue |
| C | LYS358 |
| C | LEU359 |
| C | ALA361 |
| C | PRO362 |
| C | ASP365 |
| C | GLY414 |
| C | HIS415 |
| C | GLY416 |
| C | ASP462 |
| C | CYS464 |
| C | GLU497 |
| C | ALA498 |
| C | PHE499 |
| C | GLU500 |
| C | GLN502 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 428 |
| Details | Region: {"description":"Caspase-like"} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 14 |
| Details | Motif: {"description":"Nuclear export signal"} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Active site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
