3UKM
Crystal structure of the human two pore domain potassium ion channel K2P1 (TWIK-1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D (A, B, C, D) | Potassium channel subfamily K member 1 | polymer | 280 | 31911.0 | 4 | UniProt (O00180) Pfam (PF07885) | Homo sapiens (human) | Inward rectifying potassium channel protein TWIK-1, Potassium channel KCNO1 |
| 2 | E, K, L, R (A, B, C, D) | UNDECANE | non-polymer | 156.3 | 4 | Chemie (UND) | |||
| 3 | F, G, H, I, J... (A, C) | POTASSIUM ION | non-polymer | 39.1 | 10 | Chemie (K) | |||
| 4 | S, T, U, V (A, B, C, D) | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 19 - 288 (UniProt: O00180)
| PDB | External Database | Details |
|---|---|---|
| Gly 11 | - | expression tag |
| Pro 12 | - | expression tag |
| Ser 13 | - | expression tag |
| Arg 14 | - | expression tag |
| Glu 15 | - | expression tag |
| Ala 16 | - | expression tag |
| Ser 17 | - | expression tag |
| Asn 18 | - | expression tag |
| Thr 21 | Trp 21 | engineered mutation |
| Met 22 | Cys 22 | engineered mutation |
| Gln 95 | Asn 95 | engineered mutation |
| Val 289 | - | expression tag |
| Asp 290 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 127643.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1016.2 | |
| All* | Total formula weight | 128660.2 |
