3UKM
Crystal structure of the human two pore domain potassium ion channel K2P1 (TWIK-1)
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B, C, D | Potassium channel subfamily K member 1 | polymer | 280 | 31911.0 | 4 | UniProt (O00180) Pfam (PF07885) In PDB | Homo sapiens (human) | Inward rectifying potassium channel protein TWIK-1, Potassium channel KCNO1 |
| 2 | A, B, C, D | UNDECANE | non-polymer | 156.3 | 4 | Chemie (UND) | |||
| 3 | A, C | POTASSIUM ION | non-polymer | 39.1 | 10 | Chemie (K) | |||
| 4 | water | water | 18.0 | 8 | Chemie (HOH) |
Sequence modifications
A, B, C, D: 19 - 288 (UniProt: O00180)
| PDB | External Database | Details |
|---|---|---|
| Gly 11 | - | EXPRESSION TAG |
| Pro 12 | - | EXPRESSION TAG |
| Ser 13 | - | EXPRESSION TAG |
| Arg 14 | - | EXPRESSION TAG |
| Glu 15 | - | EXPRESSION TAG |
| Ala 16 | - | EXPRESSION TAG |
| Ser 17 | - | EXPRESSION TAG |
| Asn 18 | - | EXPRESSION TAG |
| Thr 21 | Trp 21 | ENGINEERED MUTATION |
| Met 22 | Cys 22 | ENGINEERED MUTATION |
| Gln 95 | Asn 95 | ENGINEERED MUTATION |
| Val 289 | - | EXPRESSION TAG |
| Asp 290 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 127643.9 | |
| Non-Polymers* | Number of molecules | 14 |
| Total formula weight | 1016.2 | |
| All* | Total formula weight | 128660.2 |
