3UK6

Crystal Structure of the Tip48 (Tip49b) hexamer

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D, E...	RuvB-like 2	polymer	368	40796.6	12	UniProt (Q9Y230) Pfam (PF06068) Pfam (PF17856) In PDB	Homo sapiens (human)	48 kDa TATA box-binding protein-interacting protein, 48 kDa TBP-interacting protein, 51 kDa erythrocyte cytosolic protein, ECP-51, INO80 complex subunit J, Repressing pontin 52, Reptin 52, TIP49b, TIP60-associated protein 54-beta, TAP54-beta
2	A, B, C, D, E...	ADENOSINE-5'-DIPHOSPHATE	non-polymer		427.2	12	Chemie (ADP)

Sequence modifications

A, B, C, D, E, F, G, H, I, J, K, L: 1 - 235 (UniProt: Q9Y230)
A, B, C, D, E, F, G, H, I, J, K, L: 239 - 463 (UniProt: Q9Y230)

PDB	External Database	Details
Ala 236	-	expression tag
Gly 237	-	expression tag
Ala 238	-	expression tag
Leu 464	-	expression tag
Glu 465	-	expression tag
His 466	-	expression tag
His 467	-	expression tag
His 468	-	expression tag
His 469	-	expression tag
His 470	-	expression tag
His 471	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	12
	Total formula weight	489558.7
Non-Polymers*	Number of molecules	12
	Total formula weight	5126.4
All*	Total formula weight	494685.1

*Water molecules are not included.