3UEE
Crystal structure of human Survivin K62A mutant bound to N-terminal histone H3
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, C) | Baculoviral IAP repeat-containing protein 5 | polymer | 146 | 16768.0 | 2 | UniProt (O15392) Pfam (PF00653) | Homo sapiens (human) | Apoptosis inhibitor 4, Apoptosis inhibitor survivin |
| 2 | C, D (B, D) | N-terminal fragment of histone H3 | polymer | 12 | 1308.5 | 2 | UniProt (by SIFTS) (P68431) | ||
| 3 | E, F (A, C) | ZINC ION | non-polymer | 65.4 | 2 | Chemie (ZN) | |||
| 4 | G, H, I (A, C, B) | water | water | 18.0 | 30 | Chemie (HOH) |
Sequence modifications
A, C: 1 - 142 (UniProt: O15392)
| PDB | External Database | Details |
|---|---|---|
| Gly -3 | - | expression tag |
| Ser -2 | - | expression tag |
| His -1 | - | expression tag |
| Glu 0 | - | expression tag |
| Ala 62 | Lys 62 | engineered mutation |
| Lys 129 | Glu 129 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 4 |
| Total formula weight | 36153.0 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 130.8 | |
| All* | Total formula weight | 36283.8 |
