3UCR

Crystal structure of the immunoreceptor TIGIT IgV domain

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D	T cell immunoreceptor with Ig and ITIM domains	polymer	110	11977.3	4	UniProt (Q495A1) Pfam (PF07686) In PDB	Homo sapiens (human)	V-set and immunoglobulin domain-containing protein 9, V-set and transmembrane domain-containing protein 3
2	A, B	CHLORIDE ION	non-polymer		35.5	8	Chemie (CL)
3		water	water		18.0	14	Chemie (HOH)

Sequence modifications

A, B, C, D: 16 - 121 (UniProt: Q495A1)

PDB	External Database	Details
Gly 12	-	EXPRESSION TAG
Ser 13	-	EXPRESSION TAG
His 14	-	EXPRESSION TAG
His 15	-	EXPRESSION TAG

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	47909.2
Non-Polymers*	Number of molecules	8
	Total formula weight	283.6
All*	Total formula weight	48192.8

*Water molecules are not included.