3UCR
Crystal structure of the immunoreceptor TIGIT IgV domain
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005102 | molecular_function | signaling receptor binding |
| A | 0050868 | biological_process | negative regulation of T cell activation |
| B | 0005102 | molecular_function | signaling receptor binding |
| B | 0050868 | biological_process | negative regulation of T cell activation |
| C | 0005102 | molecular_function | signaling receptor binding |
| C | 0050868 | biological_process | negative regulation of T cell activation |
| D | 0005102 | molecular_function | signaling receptor binding |
| D | 0050868 | biological_process | negative regulation of T cell activation |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | BINDING SITE FOR RESIDUE CL A 2 |
| Chain | Residue |
| A | GLY83 |
| C | GLN37 |
| C | GLY83 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 3 |
| Chain | Residue |
| A | THR48 |
| A | GLN49 |
| B | ASN51 |
| B | HIS104 |
| site_id | AC3 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL A 7 |
| Chain | Residue |
| A | LEU66 |
| A | HIS69 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | BINDING SITE FOR RESIDUE CL A 8 |
| Chain | Residue |
| A | ASN51 |
| A | HIS104 |
| B | THR48 |
| B | GLN49 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 1 |
| Chain | Residue |
| B | GLY83 |
| D | GLY83 |
| site_id | AC6 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 4 |
| Chain | Residue |
| B | HIS104 |
| site_id | AC7 |
| Number of Residues | 2 |
| Details | BINDING SITE FOR RESIDUE CL B 5 |
| Chain | Residue |
| B | TYR106 |
| C | HIS104 |
| site_id | AC8 |
| Number of Residues | 1 |
| Details | BINDING SITE FOR RESIDUE CL B 6 |
| Chain | Residue |
| B | LEU66 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASN25 | |
| A | ASN94 | |
| B | ASN25 | |
| B | ASN94 | |
| C | ASN25 | |
| C | ASN94 | |
| D | ASN25 | |
| D | ASN94 |
