3UC0
Crystal structure of domain I of the envelope glycoprotein ectodomain from dengue virus serotype 4 in complex with the fab fragment of the chimpanzee monoclonal antibody 5H2
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | envelope protein | polymer | 165 | 17497.5 | 2 | UniProt (Q91AI1) Pfam (PF00869) UniProt (by SIFTS) (P09866) | Dengue virus 4 | |
| 2 | C, D (H, I) | Heavy chain, monoclonal antibody 5H2 | polymer | 236 | 25070.0 | 2 | Pan troglodytes (chimpanzee) | ||
| 3 | E, F (L, M) | Light chain, monoclonal antibody 5H2 | polymer | 215 | 23493.0 | 2 | Pan troglodytes (chimpanzee) | ||
| 4 | G (A) | GLYCEROL | non-polymer | 92.1 | 1 | Chemie (GOL) | |||
| 5 | H, I, J, K, L... (A, B, H, I, M) | SULFATE ION | non-polymer | 96.1 | 12 | Chemie (SO4) | |||
| 6 | T, U, V, W, X... (A, B, H, I, L...) | water | water | 18.0 | 343 | Chemie (HOH) |
Sequence modifications
A, B: 1 - 50 (UniProt: Q91AI1)
A, B: 135 - 190 (UniProt: Q91AI1)
A, B: 192 - 298 (UniProt: Q91AI1)
A, B: 135 - 190 (UniProt: Q91AI1)
| PDB | External Database | Details |
|---|---|---|
| Gly 51 | - | linker |
| Gly 134 | - | linker |
| PDB | External Database | Details |
|---|---|---|
| Thr 191 | - | linker |
| Pro 299 | - | expression tag |
| Phe 300 | - | expression tag |
| Glu 301 | - | expression tag |
| Asp 302 | - | expression tag |
| Asp 303 | - | expression tag |
| Asp 304 | - | expression tag |
| Asp 305 | - | expression tag |
| Lys 306 | - | expression tag |
| Ala 307 | - | expression tag |
| Gly 308 | - | expression tag |
| Trp 309 | - | expression tag |
| Ser 310 | - | expression tag |
| His 311 | - | expression tag |
| Pro 312 | - | expression tag |
| Gln 313 | - | expression tag |
| Phe 314 | - | expression tag |
| Glu 315 | - | expression tag |
| Lys 316 | - | expression tag |
| Gly 317 | - | expression tag |
| Gly 318 | - | expression tag |
| Gly 319 | - | expression tag |
| Ser 320 | - | expression tag |
| Gly 321 | - | expression tag |
| Gly 322 | - | expression tag |
| Gly 323 | - | expression tag |
| Ser 324 | - | expression tag |
| Gly 325 | - | expression tag |
| Gly 326 | - | expression tag |
| Gly 327 | - | expression tag |
| Ser 328 | - | expression tag |
| Trp 329 | - | expression tag |
| Ser 330 | - | expression tag |
| His 331 | - | expression tag |
| Pro 332 | - | expression tag |
| Gln 333 | - | expression tag |
| Phe 334 | - | expression tag |
| Glu 335 | - | expression tag |
| Lys 336 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 6 |
| Total formula weight | 132121.0 | |
| Non-Polymers* | Number of molecules | 13 |
| Total formula weight | 1244.9 | |
| All* | Total formula weight | 133365.9 |
