3UA8
Crystal Structure Analysis of a 6-Amino Quinazolinedione Sulfonamide bound to human GluR2
Entity
Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
1 | A | Glutamate receptor 2 | polymer | 263 | 29347.9 | 1 | UniProt (P42262) Pfam (PF10613) Pfam (PF00060) In PDB | Homo sapiens (human) | GluR-2, AMPA-selective glutamate receptor 2, GluR-B, GluR-K2, Glutamate receptor ionotropic, AMPA 2, GluA2 |
2 | A | N-methyl-1-{3-[(methylsulfonyl)amino]-2,4-dioxo-7-(trifluoromethyl)-1,2,3,4-tetrahydroquinazolin-6-yl}-1H-imidazole-4-carboxamide | non-polymer | 446.4 | 1 | Chemie (08W) | |||
3 | water | water | 18.0 | 244 | Chemie (HOH) |
Sequence modifications
A: 3 - 117 (UniProt: P42262)
A: 120 - 263 (UniProt: P42262)
PDB | External Database | Details |
---|---|---|
Gly 1 | - | cloning artifact |
Pro 2 | - | cloning artifact |
PDB | External Database | Details |
---|---|---|
Gly 118 | - | linker |
Thr 119 | - | linker |
Sequence viewer
Contents of the asymmetric unit
Polymers | Number of chains | 1 |
Total formula weight | 29347.9 | |
Non-Polymers* | Number of molecules | 1 |
Total formula weight | 446.4 | |
All* | Total formula weight | 29794.2 |