3UA8

Crystal Structure Analysis of a 6-Amino Quinazolinedione Sulfonamide bound to human GluR2

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0015276	molecular_function	ligand-gated monoatomic ion channel activity
A	0016020	cellular_component	membrane

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	BINDING SITE FOR RESIDUE 08W A 264

Chain	Residue
A	GLU13
A	MET196
A	TYR220
A	HOH267
A	HOH286
A	HOH290
A	HOH307
A	HOH416
A	HOH433
A	HOH448
A	HOH483
A	TYR16
A	TYR61
A	PRO89
A	LEU90
A	THR91
A	ARG96
A	THR174
A	GLU193

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20614889","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XHD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20614889","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21531559","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XHD","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"3R7X","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	1
Details	Binding site: {"evidences":[{"source":"PubMed","id":"20614889","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"21531559","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2XHD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI4
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by PKC","evidences":[{"source":"UniProtKB","id":"P19491","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	1
Details	Modified residue: {"description":"Phosphoserine; by PKG","evidences":[{"source":"UniProtKB","id":"P19491","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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