3U8D
Functionally selective inhibition of Group IIA phospholipase A2 reveals a role for vimentin in regulating arachidonic acid metabolism
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Phospholipase A2, membrane associated | polymer | 124 | 13945.0 | 2 | UniProt (P14555) Pfam (PF00068) | Homo sapiens (human) | GIIC sPLA2, Group IIA phospholipase A2, Non-pancreatic secretory phospholipase A2, NPS-PLA2, Phosphatidylcholine 2-acylhydrolase 2A |
| 2 | C, H (A, B) | (3-{[3-(2-amino-2-oxoethyl)-1-benzyl-2-ethyl-1H-indol-5-yl]oxy}propyl)phosphonic acid | non-polymer | 430.4 | 2 | Chemie (U8D) | |||
| 3 | D, E, I, J (A, B) | CALCIUM ION | non-polymer | 40.1 | 4 | Chemie (CA) | |||
| 4 | F, G, K, L (A, B) | CHLORIDE ION | non-polymer | 35.5 | 4 | Chemie (CL) | |||
| 5 | M, N (A, B) | water | water | 18.0 | 335 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 27890.0 | |
| Non-Polymers* | Number of molecules | 10 |
| Total formula weight | 1163.0 | |
| All* | Total formula weight | 29053.0 |
