3U78
E67-2 selectively inhibits KIAA1718, a human histone H3 lysine 9 Jumonji demethylase
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A (A) | Lysine-specific demethylase 7 | polymer | 397 | 46081.0 | 1 | UniProt (Q6ZMT4) Pfam (PF02373) Pfam (PF17811) | Homo sapiens (human) | KIAA1718, JmjC domain-containing histone demethylation protein 1D |
| 2 | B (A) | 2-OXOGLUTARIC ACID | non-polymer | 146.1 | 1 | Chemie (AKG) | |||
| 3 | C (A) | NICKEL (II) ION | non-polymer | 58.7 | 1 | Chemie (NI) | |||
| 4 | D (A) | CHLORIDE ION | non-polymer | 35.5 | 1 | Chemie (CL) | |||
| 5 | E (A) | SULFATE ION | non-polymer | 96.1 | 1 | Chemie (SO4) | |||
| 6 | F, G (A) | 1,2-ETHANEDIOL | non-polymer | 62.1 | 2 | Chemie (EDO) | |||
| 7 | H (A) | 7-[(5-aminopentyl)oxy]-N~4~-(1-benzylpiperidin-4-yl)-N~2~-[3-(dimethylamino)propyl]-6-methoxyquinazoline-2,4-diamine | non-polymer | 549.8 | 1 | Chemie (E67) | |||
| 8 | I (A) | water | water | 18.0 | 45 | Chemie (HOH) |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 1 |
| Total formula weight | 46081.0 | |
| Non-Polymers* | Number of molecules | 7 |
| Total formula weight | 1010.2 | |
| All* | Total formula weight | 47091.2 |
