3U53

Crystal structure of human Ap4A hydrolase

Entity

Entity ID	Chain ID	Description	Type	Chain length	Formula weight	Number of molecules	DB Name (Accession)	Biological source	Descriptive keywords
1	A, B, C, D (A, B, C, D)	Bis(5'-nucleosyl)-tetraphosphatase [asymmetrical]	polymer	155	17922.4	4	UniProt (P50583) Pfam (PF00293)	Homo sapiens (human)	asymmetrical diadenosine tetraphosphate hydrolase, Ap4A hydrolase, Ap4Aase, Nudix hydrolase
2	E, F, G, I, J... (A, B, C, D)	SULFATE ION	non-polymer		96.1	17	Chemie (SO4)
3	H (A)	GLYCEROL	non-polymer		92.1	1	Chemie (GOL)
4	W, X, Y, Z (A, B, C, D)	water	water		18.0	148	Chemie (HOH)

Sequence modifications

A, B, C, D: 1 - 147 (UniProt: P50583)

PDB	External Database	Details
Leu 148	-	expression tag
Glu 149	-	expression tag
His 150	-	expression tag
His 151	-	expression tag
His 152	-	expression tag
His 153	-	expression tag
His 154	-	expression tag
His 155	-	expression tag

Contents of the asymmetric unit

Polymers	Number of chains	4
	Total formula weight	71689.5
Non-Polymers*	Number of molecules	18
	Total formula weight	1725.2
All*	Total formula weight	73414.7

*Water molecules are not included.