3U0Z
Tetramerization dynamics of the C-terminus underlies isoform-specific cAMP-gating in HCN channels
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | polymer | 210 | 24531.1 | 2 | UniProt (O88704) Pfam (PF00027) In PDB | Mus musculus (mouse) | Brain cyclic nucleotide-gated channel 1, BCNG-1, Hyperpolarization-activated cation channel 2, HAC-2 |
| 2 | A, B | ADENOSINE-3',5'-CYCLIC-MONOPHOSPHATE | non-polymer | 329.2 | 2 | Chemie (CMP) | |||
| 3 | water | water | 18.0 | 49 | Chemie (HOH) |
Sequence modifications
A, B: 390 - 592 (UniProt: O88704)
| PDB | External Database | Details |
|---|---|---|
| Gln 383 | - | expression tag |
| Gly 384 | - | expression tag |
| Pro 385 | - | expression tag |
| Ser 386 | - | expression tag |
| Ser 387 | - | expression tag |
| Pro 388 | - | expression tag |
| Met 389 | - | expression tag |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 49062.2 | |
| Non-Polymers* | Number of molecules | 2 |
| Total formula weight | 658.4 | |
| All* | Total formula weight | 49720.6 |
