3U0X
Crystal structure of the B-specific-1,3-galactosyltransferase (GTB) in complex with compound 382
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A, B (A, B) | Histo-blood group ABO system transferase | polymer | 298 | 34758.2 | 2 | UniProt (P16442) Pfam (PF03414) | Homo sapiens (human) | Fucosylglycoprotein 3-alpha-galactosyltransferase, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-N-acetylgalactosaminyltransferase, Glycoprotein-fucosylgalactoside alpha-galactosyltransferase, Histo-blood group A transferase, A transferase, Histo-blood group B transferase, B transferase, NAGAT, Fucosylglycoprotein alpha-N-acetylgalactosaminyltransferase soluble form |
| 2 | C, N (A, B) | 1-(3-phenyl-1,2,4-thiadiazol-5-yl)piperazine | non-polymer | 246.3 | 2 | Chemie (GTI) | |||
| 3 | D, E (A) | CHLORIDE ION | non-polymer | 35.5 | 2 | Chemie (CL) | |||
| 4 | F, G, H, I, O... (A, B) | GLYCEROL | non-polymer | 92.1 | 6 | Chemie (GOL) | |||
| 5 | J, K, L, M, Q... (A, B) | SULFATE ION | non-polymer | 96.1 | 7 | Chemie (SO4) | |||
| 6 | T, U (A, B) | water | water | 18.0 | 370 | Chemie (HOH) |
Sequence modifications
A, B: 64 - 354 (UniProt: P16442)
| PDB | External Database | Details |
|---|---|---|
| Met 57 | - | expression tag |
| Ala 58 | - | expression tag |
| Ile 59 | - | expression tag |
| Gly 60 | - | expression tag |
| Glu 61 | - | expression tag |
| Phe 62 | - | expression tag |
| Met 63 | - | expression tag |
| Ser 235 | Gly 235 | SEE REMARK 999 |
| Met 266 | Leu 266 | SEE REMARK 999 |
| Ala 268 | Gly 268 | SEE REMARK 999 |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 69516.4 | |
| Non-Polymers* | Number of molecules | 17 |
| Total formula weight | 1788.6 | |
| All* | Total formula weight | 71304.9 |
