English 日本語简体中文繁體中文 한국어

✖

Menu

RCSB PDB PDBe BMRB Adv. Search Search help

Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

3U0X

Crystal structure of the B-specific-1,3-galactosyltransferase (GTB) in complex with compound 382

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0005975	biological_process	carbohydrate metabolic process
A	0016020	cellular_component	membrane
A	0016758	molecular_function	hexosyltransferase activity
B	0005975	biological_process	carbohydrate metabolic process
B	0016020	cellular_component	membrane
B	0016758	molecular_function	hexosyltransferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GTI A 1

Chain	Residue
A	ASP211
A	ASP213
A	MET214
A	PRO234
A	SER235
A	MET266
A	LEU324
A	ASP326
A	GOL356

site_id	AC2
Number of Residues	3
Details	BINDING SITE FOR RESIDUE CL A 355

Chain	Residue
A	PHE244
A	ARG248
A	LYS258

site_id	AC3
Number of Residues	2
Details	BINDING SITE FOR RESIDUE CL A 2

Chain	Residue
A	ARG68
B	GLN286

site_id	AC4
Number of Residues	8
Details	BINDING SITE FOR RESIDUE GOL A 356

Chain	Residue
A	GTI1
A	HIS233
A	PHE236
A	THR245
A	TRP300
A	GLU303
A	HOH381
A	HOH389

site_id	AC5
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL A 357

Chain	Residue
A	GLN253
A	ALA254
A	ALA287
A	HIS305
A	LYS308
A	HOH487

site_id	AC6
Number of Residues	4
Details	BINDING SITE FOR RESIDUE GOL A 5

Chain	Residue
A	ASP326
A	GLN328
A	PRO345
A	HOH485

site_id	AC7
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL A 6

Chain	Residue
A	ASN294
A	GLY295
A	HOH476
B	GLU242
B	PHE244
B	ARG248
B	LYS258

site_id	AC8
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 358

Chain	Residue
A	LYS82
A	PRO333
A	ALA334
A	HOH361
A	HOH407

site_id	AC9
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 3

Chain	Residue
A	GLN169
A	SER171
A	ARG199
A	HOH398
A	HOH458

site_id	BC1
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 A 359

Chain	Residue
A	HIS140
A	HIS140
A	VAL143
A	HIS219
A	HOH362
A	HOH491
A	HOH505

site_id	BC2
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 A 9

Chain	Residue
A	ARG249
A	GLY295
A	ILE296
A	GLU297
B	LYS258

site_id	BC3
Number of Residues	9
Details	BINDING SITE FOR RESIDUE GTI B 1

Chain	Residue
B	ASP211
B	ASP213
B	MET214
B	SER235
B	MET266
B	LEU324
B	ASP326
B	LEU329
B	LEU330

site_id	BC4
Number of Residues	6
Details	BINDING SITE FOR RESIDUE GOL B 3

Chain	Residue
B	HIS233
B	PHE236
B	THR245
B	TRP300
B	GLU303
B	HOH408

site_id	BC5
Number of Residues	7
Details	BINDING SITE FOR RESIDUE GOL B 4

Chain	Residue
B	GLN253
B	ALA254
B	ALA287
B	HIS305
B	LYS308
B	TYR309
B	HOH467

site_id	BC6
Number of Residues	3
Details	BINDING SITE FOR RESIDUE SO4 B 2

Chain	Residue
B	SER171
B	ARG199
B	HOH430

site_id	BC7
Number of Residues	5
Details	BINDING SITE FOR RESIDUE SO4 B 355

Chain	Residue
B	LYS139
B	HIS140
B	VAL143
B	HIS219
B	HOH414

site_id	BC8
Number of Residues	7
Details	BINDING SITE FOR RESIDUE SO4 B 12

Chain	Residue
B	HOH43
B	PHE121
B	ARG188
B	ILE192
B	CYS209
B	GLY267
B	PHE270

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	ACT_SITE: Nucleophile => ECO:0000250\|UniProtKB:P14769

Chain	Residue	Details
A	GLU303
B	GLU303

site_id	SWS_FT_FI2
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:12198488, ECO:0000269\|PubMed:12972418, ECO:0000269\|PubMed:15475562, ECO:0000269\|PubMed:16326711, ECO:0000269\|PubMed:17259183, ECO:0007744\|PDB:1LZI, ECO:0007744\|PDB:1LZJ, ECO:0007744\|PDB:1R7Y, ECO:0007744\|PDB:1R80, ECO:0007744\|PDB:1R81, ECO:0007744\|PDB:1R82, ECO:0007744\|PDB:1WT3, ECO:0007744\|PDB:1ZI5, ECO:0007744\|PDB:1ZJ2, ECO:0007744\|PDB:1ZJO, ECO:0007744\|PDB:1ZJP, ECO:0007744\|PDB:2A8U, ECO:0007744\|PDB:2A8W, ECO:0007744\|PDB:2O1H, ECO:0007744\|PDB:2RIX, ECO:0007744\|PDB:2RJ0, ECO:0007744\|PDB:2RJ1, ECO:0007744\|PDB:2RJ4, ECO:0007744\|PDB:2RJ5, ECO:0007744\|PDB:2RJ7, ECO:0007744\|PDB:2RJ8, ECO:0007744\|PDB:2RJ9, ECO:0007744\|PDB:2Y7A, ECO:0007744\|PDB:3I0D, ECO:0007744\|PDB:3I0F, ECO:0007744\|PDB:3I0G, ECO:0007744\|PDB:3I0I, ECO:0007744\|PDB:3I0K, ECO:0007744\|PDB:3I0L, ECO:0007744\|PDB:3IOI, ECO:0007744\|PDB:3IOJ, ECO:0007744\|PDB:3SX3, ECO:0007744\|PDB:3SX5, ECO:0007744\|PDB:3SX7, ECO:0007744\|PDB:3SX8, ECO:0007744\|PDB:3SXA, ECO:0007744\|PDB:3SXB, ECO:0007744\|PDB:3SXC, ECO:0007744\|PDB:3SXD, ECO:0007744\|PDB:3SXE, ECO:0007744\|PDB:3SXG, ECO:0007744\|PDB:3U0Y, ECO:0007744\|PDB:3V0L, ECO:0007744\|PDB:3V0N, ECO:0007744\|PDB:3V0Q, ECO:0007744\|PDB:3ZGF, ECO:0007744\|PDB:3ZGG, ECO:0007744\|PDB:4C2S, ECO:0007744\|PDB:4FQW, ECO:0007744\|PDB:4FRA, ECO:0007744\|PDB:4FRB, ECO:0007744\|PDB:4FRD, ECO:0007744\|PDB:4FRE, ECO:0007744\|PDB:4FRH, ECO:0007744\|PDB:4FRL, ECO:0007744\|PDB:4FRM, ECO:0007744\|PDB:4FRO, ECO:0007744\|PDB:4FRP, ECO:0007744\|PDB:4FRQ, ECO:0007744\|PDB:4GBP, ECO:0007744\|PDB:4KC1, ECO:0007744\|PDB:4KC2, ECO:0007744\|PDB:4KC4

Chain	Residue	Details
A	PHE121
B	PHE121

site_id	SWS_FT_FI3
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:12198488, ECO:0000269\|PubMed:12972418, ECO:0000269\|PubMed:15475562, ECO:0000269\|PubMed:16326711, ECO:0000269\|PubMed:17259183, ECO:0007744\|PDB:1LZI, ECO:0007744\|PDB:1LZJ, ECO:0007744\|PDB:1R7Y, ECO:0007744\|PDB:1R80, ECO:0007744\|PDB:1R81, ECO:0007744\|PDB:1R82, ECO:0007744\|PDB:1WT1, ECO:0007744\|PDB:1WT2, ECO:0007744\|PDB:1WT3, ECO:0007744\|PDB:1ZI5, ECO:0007744\|PDB:1ZJ2, ECO:0007744\|PDB:1ZJO, ECO:0007744\|PDB:1ZJP, ECO:0007744\|PDB:2A8U, ECO:0007744\|PDB:2A8W, ECO:0007744\|PDB:2O1H, ECO:0007744\|PDB:2RIX, ECO:0007744\|PDB:2RJ0, ECO:0007744\|PDB:2RJ1, ECO:0007744\|PDB:2RJ4, ECO:0007744\|PDB:2RJ5, ECO:0007744\|PDB:2RJ7, ECO:0007744\|PDB:2RJ8, ECO:0007744\|PDB:2RJ9, ECO:0007744\|PDB:2Y7A, ECO:0007744\|PDB:3I0D, ECO:0007744\|PDB:3I0F, ECO:0007744\|PDB:3I0G, ECO:0007744\|PDB:3I0I, ECO:0007744\|PDB:3I0K, ECO:0007744\|PDB:3I0L, ECO:0007744\|PDB:3IOI, ECO:0007744\|PDB:3IOJ, ECO:0007744\|PDB:3SX3, ECO:0007744\|PDB:3SX5, ECO:0007744\|PDB:3SX7, ECO:0007744\|PDB:3SX8, ECO:0007744\|PDB:3SXA, ECO:0007744\|PDB:3SXB, ECO:0007744\|PDB:3SXC, ECO:0007744\|PDB:3SXD, ECO:0007744\|PDB:3SXE, ECO:0007744\|PDB:3SXG, ECO:0007744\|PDB:3U0Y, ECO:0007744\|PDB:3V0L, ECO:0007744\|PDB:3V0N, ECO:0007744\|PDB:3V0Q, ECO:0007744\|PDB:3ZGF, ECO:0007744\|PDB:3ZGG, ECO:0007744\|PDB:4C2S, ECO:0007744\|PDB:4FQW, ECO:0007744\|PDB:4FRA, ECO:0007744\|PDB:4FRB, ECO:0007744\|PDB:4FRD, ECO:0007744\|PDB:4FRE, ECO:0007744\|PDB:4FRH, ECO:0007744\|PDB:4FRL, ECO:0007744\|PDB:4FRM, ECO:0007744\|PDB:4FRO, ECO:0007744\|PDB:4FRP, ECO:0007744\|PDB:4FRQ, ECO:0007744\|PDB:4GBP, ECO:0007744\|PDB:4KC1, ECO:0007744\|PDB:4KC2, ECO:0007744\|PDB:4KC4

Chain	Residue	Details
A	TYR126
B	TYR126

site_id	SWS_FT_FI4
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269\|PubMed:12198488, ECO:0000269\|PubMed:12972418, ECO:0000269\|PubMed:16326711, ECO:0000269\|PubMed:17259183, ECO:0007744\|PDB:1LZJ, ECO:0007744\|PDB:1R80, ECO:0007744\|PDB:1ZJ2, ECO:0007744\|PDB:1ZJP, ECO:0007744\|PDB:2A8U, ECO:0007744\|PDB:2O1H, ECO:0007744\|PDB:2RIX, ECO:0007744\|PDB:2RJ0, ECO:0007744\|PDB:2RJ1, ECO:0007744\|PDB:2RJ4, ECO:0007744\|PDB:2RJ5, ECO:0007744\|PDB:2RJ7, ECO:0007744\|PDB:2RJ8, ECO:0007744\|PDB:2RJ9, ECO:0007744\|PDB:3I0F, ECO:0007744\|PDB:3IOI, ECO:0007744\|PDB:3IOJ, ECO:0007744\|PDB:3SX3, ECO:0007744\|PDB:3SX5, ECO:0007744\|PDB:3SX7, ECO:0007744\|PDB:3SXA, ECO:0007744\|PDB:3SXB, ECO:0007744\|PDB:3SXD, ECO:0007744\|PDB:3SXE, ECO:0007744\|PDB:3SXG, ECO:0007744\|PDB:3U0Y, ECO:0007744\|PDB:3V0L, ECO:0007744\|PDB:3V0M, ECO:0007744\|PDB:3V0N, ECO:0007744\|PDB:3V0O, ECO:0007744\|PDB:3V0P, ECO:0007744\|PDB:3V0Q, ECO:0007744\|PDB:3ZGF, ECO:0007744\|PDB:3ZGG, ECO:0007744\|PDB:4C2S, ECO:0007744\|PDB:4FRB, ECO:0007744\|PDB:4FRD, ECO:0007744\|PDB:4FRH, ECO:0007744\|PDB:4FRL, ECO:0007744\|PDB:4FRO, ECO:0007744\|PDB:4FRP, ECO:0007744\|PDB:4FRQ, ECO:0007744\|PDB:4GBP

Chain	Residue	Details
A	ASP211
A	ASP213
B	ASP211
B	ASP213

site_id	SWS_FT_FI5
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:16326711, ECO:0007744\|PDB:1ZHJ, ECO:0007744\|PDB:1ZI3, ECO:0007744\|PDB:1ZI4, ECO:0007744\|PDB:1ZI5, ECO:0007744\|PDB:1ZJ1, ECO:0007744\|PDB:1ZJ2, ECO:0007744\|PDB:1ZJ3, ECO:0007744\|PDB:2A8U, ECO:0007744\|PDB:2RJ1, ECO:0007744\|PDB:2RJ4, ECO:0007744\|PDB:2RJ7, ECO:0007744\|PDB:2RJ8, ECO:0007744\|PDB:2RJ9, ECO:0007744\|PDB:3SX3, ECO:0007744\|PDB:3SX7, ECO:0007744\|PDB:3SX8, ECO:0007744\|PDB:3SXA, ECO:0007744\|PDB:3SXG, ECO:0007744\|PDB:3V0M, ECO:0007744\|PDB:3V0N, ECO:0007744\|PDB:3V0O, ECO:0007744\|PDB:3V0P, ECO:0007744\|PDB:3V0Q, ECO:0007744\|PDB:3ZGF, ECO:0007744\|PDB:4C2S, ECO:0007744\|PDB:4FQW, ECO:0007744\|PDB:4FRA, ECO:0007744\|PDB:4FRB, ECO:0007744\|PDB:4FRD, ECO:0007744\|PDB:4FRE, ECO:0007744\|PDB:4FRH, ECO:0007744\|PDB:4FRL, ECO:0007744\|PDB:4FRM, ECO:0007744\|PDB:4FRO, ECO:0007744\|PDB:4FRP, ECO:0007744\|PDB:4FRQ, ECO:0007744\|PDB:4GBP, ECO:0007744\|PDB:4KC1, ECO:0007744\|PDB:4KC2, ECO:0007744\|PDB:4KC4

Chain	Residue	Details
A	HIS233
B	HIS233

site_id	SWS_FT_FI6
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:12972418, ECO:0000269\|PubMed:15475562, ECO:0000269\|PubMed:16326711, ECO:0007744\|PDB:1R7T, ECO:0007744\|PDB:1R7U, ECO:0007744\|PDB:1WT2, ECO:0007744\|PDB:1ZHJ, ECO:0007744\|PDB:1ZI3, ECO:0007744\|PDB:1ZI4, ECO:0007744\|PDB:1ZI5, ECO:0007744\|PDB:1ZIZ, ECO:0007744\|PDB:1ZJ0, ECO:0007744\|PDB:1ZJ1, ECO:0007744\|PDB:1ZJ2, ECO:0007744\|PDB:1ZJ3, ECO:0007744\|PDB:2A8U, ECO:0007744\|PDB:2RIY, ECO:0007744\|PDB:2RJ1, ECO:0007744\|PDB:2RJ4, ECO:0007744\|PDB:2RJ6, ECO:0007744\|PDB:2RJ7, ECO:0007744\|PDB:2RJ8, ECO:0007744\|PDB:2RJ9, ECO:0007744\|PDB:3SX3, ECO:0007744\|PDB:3SX5, ECO:0007744\|PDB:3SX7, ECO:0007744\|PDB:3SX8, ECO:0007744\|PDB:3SXA, ECO:0007744\|PDB:3SXB, ECO:0007744\|PDB:3SXC, ECO:0007744\|PDB:3SXD, ECO:0007744\|PDB:3SXE, ECO:0007744\|PDB:3SXG, ECO:0007744\|PDB:3V0M, ECO:0007744\|PDB:3V0O, ECO:0007744\|PDB:3V0P, ECO:0007744\|PDB:3V0Q, ECO:0007744\|PDB:4C2S, ECO:0007744\|PDB:4FQW, ECO:0007744\|PDB:4FRA, ECO:0007744\|PDB:4FRB, ECO:0007744\|PDB:4FRD, ECO:0007744\|PDB:4FRE, ECO:0007744\|PDB:4FRH, ECO:0007744\|PDB:4FRL, ECO:0007744\|PDB:4FRM, ECO:0007744\|PDB:4FRO, ECO:0007744\|PDB:4FRP, ECO:0007744\|PDB:4FRQ, ECO:0007744\|PDB:4GBP, ECO:0007744\|PDB:4KC1, ECO:0007744\|PDB:4KC2, ECO:0007744\|PDB:4KC4

Chain	Residue	Details
A	THR245
B	THR245

site_id	SWS_FT_FI7
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:12972418, ECO:0000269\|PubMed:15475562, ECO:0000269\|PubMed:16326711, ECO:0007744\|PDB:1R7T, ECO:0007744\|PDB:1R7U, ECO:0007744\|PDB:1WT2, ECO:0007744\|PDB:1ZHJ, ECO:0007744\|PDB:1ZI3, ECO:0007744\|PDB:1ZI4, ECO:0007744\|PDB:1ZI5, ECO:0007744\|PDB:1ZIZ, ECO:0007744\|PDB:1ZJ0, ECO:0007744\|PDB:1ZJ1, ECO:0007744\|PDB:1ZJ2, ECO:0007744\|PDB:1ZJ3, ECO:0007744\|PDB:2A8U, ECO:0007744\|PDB:2RIY, ECO:0007744\|PDB:2RJ1, ECO:0007744\|PDB:2RJ4, ECO:0007744\|PDB:2RJ6, ECO:0007744\|PDB:2RJ7, ECO:0007744\|PDB:2RJ8, ECO:0007744\|PDB:2RJ9, ECO:0007744\|PDB:3I0G, ECO:0007744\|PDB:3I0L, ECO:0007744\|PDB:3IOI, ECO:0007744\|PDB:3SX3, ECO:0007744\|PDB:3SX5, ECO:0007744\|PDB:3SX7, ECO:0007744\|PDB:3SX8, ECO:0007744\|PDB:3SXA, ECO:0007744\|PDB:3SXB, ECO:0007744\|PDB:3SXC, ECO:0007744\|PDB:3SXD, ECO:0007744\|PDB:3SXE, ECO:0007744\|PDB:3SXG, ECO:0007744\|PDB:3V0L, ECO:0007744\|PDB:3V0M, ECO:0007744\|PDB:3V0O, ECO:0007744\|PDB:3V0P, ECO:0007744\|PDB:3V0Q, ECO:0007744\|PDB:3ZGG, ECO:0007744\|PDB:4C2S, ECO:0007744\|PDB:4FQW, ECO:0007744\|PDB:4FRA, ECO:0007744\|PDB:4FRB, ECO:0007744\|PDB:4FRD, ECO:0007744\|PDB:4FRE, ECO:0007744\|PDB:4FRH, ECO:0007744\|PDB:4FRL, ECO:0007744\|PDB:4FRM, ECO:0007744\|PDB:4FRO, ECO:0007744\|PDB:4FRP, ECO:0007744\|PDB:4FRQ, ECO:0007744\|PDB:4GBP, ECO:0007744\|PDB:4KC1, ECO:0007744\|PDB:4KC2, ECO:0007744\|PDB:4KC4

Chain	Residue	Details
A	GLU303
B	GLU303

site_id	SWS_FT_FI8
Number of Residues	2
Details	BINDING: BINDING => ECO:0000269\|PubMed:12972418, ECO:0000269\|PubMed:16326711, ECO:0007744\|PDB:1R7T, ECO:0007744\|PDB:1ZI4, ECO:0007744\|PDB:1ZI5, ECO:0007744\|PDB:1ZJ2, ECO:0007744\|PDB:1ZJ3, ECO:0007744\|PDB:2RIY, ECO:0007744\|PDB:2RJ1, ECO:0007744\|PDB:2RJ4, ECO:0007744\|PDB:2RJ6, ECO:0007744\|PDB:2RJ7, ECO:0007744\|PDB:2RJ8, ECO:0007744\|PDB:2RJ9, ECO:0007744\|PDB:3V0M, ECO:0007744\|PDB:3V0O, ECO:0007744\|PDB:3V0P, ECO:0007744\|PDB:3V0Q, ECO:0007744\|PDB:4C2S, ECO:0007744\|PDB:4KC1, ECO:0007744\|PDB:4KC2, ECO:0007744\|PDB:4KC4

Chain	Residue	Details
A	ASP326
B	ASP326

site_id	SWS_FT_FI9
Number of Residues	2
Details	CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255

Chain	Residue	Details
A	ASN113
B	ASN113

224201

PDB entries from 2024-08-28

PDB statistics

PDBj update info

Contact PDBj

numon