3TWU
Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1
Entity
| Entity ID | Chain ID | Description | Type | Chain length | Formula weight | Number of molecules | DB Name (Accession) | Biological source | Descriptive keywords |
| 1 | A | Tankyrase-2 | polymer | 167 | 17995.3 | 1 | UniProt (Q9H2K2) Pfam (PF12796) In PDB | Homo sapiens (human) | TANK2, Poly [ADP-ribose] polymerase 5B, TNKS-2, TRF1-interacting ankyrin-related ADP-ribose polymerase 2, Tankyrase II, Tankyrase-like protein, Tankyrase-related protein |
| 2 | B | Induced myeloid leukemia cell differentiation protein Mcl-1 | polymer | 16 | 1719.0 | 1 | UniProt (Q07820) In PDB | Homo sapiens | Bcl-2-like protein 3, Bcl2-L-3, Bcl-2-related protein EAT/mcl1, mcl1/EAT |
| 3 | water | water | 18.0 | 109 | Chemie (HOH) |
Sequence modifications
A: 488 - 649 (UniProt: Q9H2K2)
| PDB | External Database | Details |
|---|---|---|
| Gly 483 | - | EXPRESSION TAG |
| Ala 484 | - | EXPRESSION TAG |
| Met 485 | - | EXPRESSION TAG |
| Gly 486 | - | EXPRESSION TAG |
| Ser 487 | - | EXPRESSION TAG |
Sequence viewer
Contents of the asymmetric unit
| Polymers | Number of chains | 2 |
| Total formula weight | 19714.3 | |
| All* | Total formula weight | 19714.3 |
