3TWU

Crystal structure of ARC4 from human Tankyrase 2 in complex with peptide from human MCL1

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0003950	molecular_function	NAD+ ADP-ribosyltransferase activity
A	0016055	biological_process	Wnt signaling pathway
A	0032212	biological_process	positive regulation of telomere maintenance via telomerase
A	0051225	biological_process	spindle assembly

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	32
Details	Repeat: {"description":"ANK 10"}

Chain

Residue

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site_id	SWS_FT_FI2
Number of Residues	32
Details	Repeat: {"description":"ANK 11"}

Chain

Residue

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site_id	SWS_FT_FI3
Number of Residues	32
Details	Repeat: {"description":"ANK 12"}

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Residue

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site_id	SWS_FT_FI4
Number of Residues	8
Details	Region: {"description":"HIF1AN-binding","evidences":[{"source":"PubMed","id":"21251231","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI5
Number of Residues	2
Details	Modified residue: {"description":"(3S)-3-hydroxyasparagine; by HIF1AN; partial","evidences":[{"source":"PubMed","id":"18936059","evidenceCode":"ECO:0000269"}]}

Chain

Residue

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site_id	SWS_FT_FI6
Number of Residues	1
Details	Modified residue: {"description":"(3S)-3-hydroxyhistidine; by HIF1AN; partial","evidences":[{"source":"PubMed","id":"21251231","evidenceCode":"ECO:0000269"}]}

Chain

Residue

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